Urinary α1-microglobulin (α1-MG)

1-1-microglobulin is a glycoprotein that is mainly synthesized in liver and lymphoid tissues and is widely distributed on body fluids and lymphocyte membrane surfaces. Urinary α1-MG has two types, free type and combined type. The free form can be filtered by the renal tubules, and the combined type cannot pass through the renal tubules. Pathological increase is seen in renal tubular damage, such as chronic renal failure, and there is a binding type in the urine. When α1—MG, it indicates that the glomerular filtration membrane is damaged. Urine α1-MG can be used as an early sensitive indicator of translational kidney injury. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Combined with serum α1-microglobulin decreased, suggesting severe liver damage, seen in patients with liver disease. Normal value: α1-MG: 0-6mg/24h Above normal: Pyelonephritis, potassium-defleasing nephritis, renal vascular disease, myeloma, heavy metal poisoning, etc. negative: Positive: Tips: It is not advisable to have a urine test during a cold. Generally, you can do it after a week. It is also best not to leave urine for diarrhea. Normal value α1-MG<6mg/24h. Clinical significance (1) Elevation: pyelonephritis, potassium-defleasing nephritis, renal vascular disease, myeloma, heavy metal poisoning, etc. (2) reduction: combined with serum α1-microglobulin decreased, suggesting severe liver damage, seen in patients with liver disease. High results may be diseases: cirrhosis precautions 1, stay 24 hours of urine on the same day of normal diet, normal activities, do not deliberately drink too much water, neither can stay in bed nor too vigorous exercise. 2. When the weather is hot, some hospitals require preservatives to prevent the urine from deteriorating. The first urine collected after emptying the bladder at 7:00 on the first day is added to the container together with the preservative. However, it is best to add nothing, and the collected urine is most scientifically stored in the refrigerator. 3, during the cold period should not be done urine test, generally wait for a cold after a week to do. It is also best not to leave urine for diarrhea. Inspection process Go to the right amount of middle urine and send it for inspection. Not suitable for the crowd It is not advisable to have a urine test during a cold, and generally wait for a cold for a week. Adverse reactions and risks No.

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