Urinary C-peptide

The same CP does not interfere with exogenous insulin and insulin antibodies, so it is one of the most realistic, comprehensive and sensitive indicators for determining B cell function. C-Peptide, also known as a linker peptide, is a secreted product of islet beta cells, which shares a common precursor with insulin, proinsulin. A molecule of proinsulin is cleaved into a molecule of insulin and a molecule of C peptide. Basic Information Specialist Category: Inspection Category: Urine/Kidney Function Test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Type 1 diabetes. Normal value: Urinary C peptide: 45-117μg/24h Above normal: Islet cell tumor, insulin autoimmune syndrome. negative: Positive: Tips: When you take the urine for inspection, you need to indicate whether you are taking insulin treatment. Normal value 45 ~ 117 μg / 24h. Clinical significance (1) elevated: islet cell tumor, insulin autoimmune syndrome. (2) Reduction: Type 1 diabetes. Low results may be diseases: Type I diabetes, high results of insulinoma may be diseases: Precautions for diabetes in the elderly When you take the urine for examination, you need to indicate whether you are taking insulin. Inspection process The radioactive label 125I-CP and the C-peptide in the specimen (or standard) are competitively bound to the limited C-peptide antibody. After equilibration, the separating agent is added to determine the radioactivity in the precipitate, and the content of the C-peptide in the specimen is Negative correlation. Not suitable for the crowd No taboos. Adverse reactions and risks No.

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