Urine amino acid nitrogen

One or more amino acids in the urine are called amino aciduria. With the understanding of genetic diseases, the examination of amino acid urine has received attention. Due to the higher renal threshold of plasma amino acids, only a small amount of amino acids can be found in normal urine. Even if it is filtered out by the glomerulus, it is easily reabsorbed by the renal tubules. The amino acids in urine are divided into two types, free and combined, wherein the free form is about 1.1g/24h and the combined type is about 2g/24h. The binding type is a product in which an amino acid is converted in vivo, such as glycine and benzoic acid, to form hippuric acid; N-2 acylglutamic acid is combined with benzoic acid to form phenylacetylglutamate. The amino acid content in normal urine is significantly different from that in plasma. The amino acids in urine are mainly glycine, histidine, lysine, serine and aminoethanesulfonic acid. The amount of excretion is quite different in the age group. The discharge of some amino acid children is higher than that of adults, which may be due to the immature development of renal tubules in children and the decrease in reabsorption. However, adult β-aminoisobutyric acid, glycine, aspartic acid and so on are significantly higher than children. In addition to age, urinary amino acids are also significantly different due to dietary, genetic and physiological changes. For example, urinary histidine and threonine can be significantly increased during pregnancy. Examination of amino acids and their metabolites in urine can be used as screening tests for amino acid abnormalities in hereditary diseases. Increased concentration of amino acids in the blood can spill over the urine and is seen in certain congenital diseases. Such as due to kidney damage or drug damage, renal tubular reabsorption, renal threshold decreased, resulting in kidney-type amino acid urine, the patient's blood amino acid concentration is not high. The amino acid nitrogen in serum accounts for about 25% of non-protein nitrogen. Basic Information Specialist classification: growth and development check classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: No clinical significance. Normal value: Urinary amino acid nitrogen: 3.6-14.2mmol/24h Above normal: Primary and secondary amino aciduria, nephropathy, diabetes, vitamin D deficiency (rickets), vitamin C deficiency, Fanconi syndrome (Fanconi syndrome), galactosemia, glycogen storage disease, Hepatolenticular degeneration, ocular-brain-renal syndrome (Lowe syndrome), and the like. negative: Positive: Tips: The primary factors for the increase in the total amount of amino acids in the urine are mostly due to elevated plasma concentrations of certain amino acids or other transport carrier defects. Normal value 3.6 to 14.2 mmol/24 h (50 to 200 mg/24 h). Clinical significance (1) Elevation: primary and secondary amino aciduria, nephropathy, diabetes, vitamin D deficiency (rickets), vitamin C deficiency, Fanconi syndrome (Fanconi syndrome), galactosemia, Glycogen storage disease, Wilson's disease, eye-brain-renal syndrome (Lowe syndrome), etc. (2) Reduced without clinical significance. High results may be diseases: extracellular cholesterol syndrome in children, radiation disease precautions The primary factors for the increase in the total amount of amino acids in the urine are mostly due to elevated plasma concentrations of certain amino acids or defects in other transport carriers. Inspection process Urease Boehm colorimetry. Not suitable for the crowd Generally no taboos. Adverse reactions and risks No.

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