Urine beta-hydroxybutyrate

Fatty acids can be completely oxidized to carbon dioxide and water in many tissues such as muscle. However, in the liver, the oxidation of fatty acids is incomplete, and some intermediates of oxidative decomposition of fatty acids, such as acetoacetic acid, β-hydroxybutyric acid and acetone, are collectively referred to as ketone bodies. They are normal intermediates in the oxidative decomposition of fatty acids and are present in small amounts in both tissue cells and blood. However, when the body is metabolically dysfunctional (such as severe diabetes, starvation, etc.), fat becomes the main energy-supplying substance in the body. At this time, there is a balance between the formation of ketone bodies and oxidative decomposition, and there are too many ketone bodies. For ketosis. Determination of acetoacetate, β-hydroxybutyrate, and acetone contributes to the diagnosis of ketosis. Basic Information Specialist classification: growth and development check classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: (1) In the case of diabetic ketoacidosis, the urinary ketone body is strongly positive. When the renal function is severely damaged and the renal threshold is increased, the urinary ketone body can be reduced or even completely disappeared. (2) Premature vomiting, eclampsia, severe illness, inability to eat, digestive dysfunction and other ketone bodies are positive. Tips: If the control tube (B tube) is positive, it indicates that the evaporation time is not enough, and there are acetone and acetoacetic acid in the urine. Normal value negative. Clinical significance (1) In the case of diabetic ketoacidosis, the urinary ketone body is strongly positive. When the renal function is severely damaged and the renal threshold is increased, the urinary ketone body can be reduced or even completely disappeared. (2) Premature vomiting, eclampsia, severe illness, inability to eat, digestive dysfunction and other ketone bodies are positive. Positive results may be diseases: diabetic ketoacidosis, pregnancy vomiting, preeclampsia precautions (1) If the control tube (B tube) is positive, it indicates that the evaporation time is insufficient, and acetone and acetoacetic acid are also present in the urine. (2) After adding hydrogen peroxide (H2O2), just warm it up slightly. Other precautions are the same as the Rothera method. (3) The ketone body discharged from the urine is mainly acetoacetic acid, and the amount of β-hydroxybutyric acid excretion in the urine is significantly increased when the amount is large. Found in severe acidosis. Inspection process (1) Take 20ml of urine in a small beaker, add 2~3 drops of glacial acetic acid, dilute with the same amount of water, and then boil and concentrate to the original volume (about 20ml). At this point acetone and acetoacetic acid have been removed. (2) Divide the boiled urine into two test tubes, labeled "B" and "T" respectively. Add 1 ml of 3% H2O2 solution to the "T" tube and heat for 1 min. After cooling, the two tubes "T" and "B" were simultaneously inspected according to the Rothera method. (3) Judgment of results: "T" tube was positive, "B" tube was negative, indicating the presence of beta hydroxybutyrate. Not suitable for the crowd Generally no taboos. Adverse reactions and risks No.

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