Thrombocytosis

Introduction Thrombocytopenia Thrombocytopenia is a disease in which abnormal blood clots are caused by increased platelet production. Clinically rare, can be divided into primary and secondary (reactive). Platelet counts are mostly detected by automated blood cell analyzers, and a few are still examined by microscopic visual inspection. The reference value range (100 ~ 300) × 10 ^ 9 / L, when the platelet count is less than 100 × 10 ^ 9 / L, called thrombocytopenia, if greater than 400 × 10 ^ 9 / L + called thrombocytosis. Thrombocytopenia usually occurs in people over the age of 50.

Cause

Thrombocytopenia may be caused by two aspects: primary thrombocytosis caused by clonal proliferation of a single abnormal pluripotent stem cell; inflammatory disease, malignant tumor, post-spleen and functional spleen-free, drug-induced Secondary thrombocytosis.

an examination

Related inspection

Blood routine blood test, white clay, partial thromboplastin time, plasma -platelet globulin serum acid phosphatase isoenzyme

Thrombocytopenia examination

1. Clinical manifestations: tingling in the hands and feet and other abnormal sensations, cold fingertips, headache, weakness and dizziness. Hemorrhagic symptoms are often mild, including snoring, cyanosis, gingival bleeding, or gastrointestinal bleeding. Liver and spleen can increase.

2. Platelet count: >1000×109/L.

Differential diagnosis

Increased platelet aggregation: Platelet aggregation is one of the main functions of platelets, and malignant tumors enhance platelet aggregation.

Thrombocytopenia: A symptom of a decrease or lack of platelet unit cells in the blood. Thrombocytopenia is usually caused by antibodies formed by the body attacking its own platelets.

Thrombocytopenic purpura: divided into primary and secondary. Primary thrombocytopenic purpura is an immune syndrome that is a common hemorrhagic disease. It is characterized by the presence of anti-platelet antibodies in the blood circulation, causing excessive destruction of platelets and causing purpura, while megakaryocytes in the bone marrow are normal or increased, and are immature. According to the age of onset, clinical manifestations, platelet count, length of disease and prognosis, the disease was divided into acute and chronic, and the pathogenesis and performance of the two were significantly different.

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