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Elevated serum TG levels

Introduction
Cause
Examine
Diagnosis

Introduction

Introduction Serum triglyceride (TG) is one of the components of blood esters. Triglycerides are in a dynamic equilibrium in the human body. The content of blood esters can vary with changes in the diet and varies widely. In addition, its content increases with age, especially in middle-aged and elderly people whose body weight exceeds the standard. Triglycerides fluctuate widely, depending on age, gender, dietary structure and lifestyle.

Cause

Cause

Reasons for elevated serum TG levels

Triglycerides fluctuate widely, depending on age, gender, dietary structure and lifestyle. Triglycerides in the human body are mainly synthesized in liver and adipose tissue, and can also be synthesized from food through small intestinal mucosa. Triglycerides in serum are mainly found in very low density lipoprotein (VLDL) and chylomicrons (CM). Hypertriglyceridemia is one of the risk factors for cardiovascular disease.

Examine

an examination

Related inspection

blood test

Examination of elevated serum TG levels

Clinically tested serum triglyceride concentrations are mainly used for hyperlipidemia, pancreatitis, liver and kidney disease, atherosclerosis and nutritional evaluation.

Diagnosis

Differential diagnosis

Symptoms of elevated serum TG levels

Elevated serum alpha-fetoprotein: A fetal protein (AFP) is an important component of fetal serum in the embryonic period, with a serum content of up to 1 mg per ml. However, in adult serum, its content is only a nanogram level. However, after adults with primary liver cancer or teratomas, the level of serum AFP will increase again, so AFP is a carcinoembryonic anti-protein. As early as the 1950s, scholars found AFP in fetal serum. In the 1960s, alpha-fetoprotein was also found in the serum of human or animal with primary liver cancer. Later, this discovery was gradually used for clinical diagnosis of liver cancer. In addition to embryonal cancer, AFP is highly specific for the diagnosis of liver cancer.

Serum testosterone concentration is significantly increased: the normal menstrual cycle follicular phase, the average serum testosterone concentration is 0.43ng / ml, the high limit is 0.68ng / ml, such as more than 0.7ng / m1 (equal to 2.44nmol / L), known as high Testosteroneemia, or hyperandrogenism.

Increased serum calcitonin levels: Serum calcitonin is a hormone secreted by thyroid follicular cells. When it is elevated for some reason, it can increase the amount of calcium excreted by the kidneys and lower the blood calcium concentration. Calcitonin is a thirty-two peptide containing a disulfide bond and has a molecular weight of 3,400. Normal human serum has a calcitonin concentration of 10-20 ng/L and a plasma half-life of less than 1 h, which is mainly degraded and excreted in the kidney. The main role of calcitonin is to lower blood calcium and blood phosphorus. The main target organ is bone, which also has a certain effect on the kidney.

High levels of aspartate aminotransferase (AST) in serum: Aspartate aminotransferase, also known as aspartate aminotransferase, abbreviation AST, is a kind of liver function. Transaminase is an indispensable "catalyst" in the body's metabolic process and is mainly found in hepatocytes. When hepatocytes develop inflammation, necrosis, poisoning, etc., causing damage to the liver cells, the transaminase is released into the blood, causing the serum transaminase to rise.