Angioedema

Introduction Angioedema, also known as giant urticaria, also known as quince edema, is due to a decrease in the level of C1 esterase inhibitors in the blood and tissues, or inactivity. It is the involvement of small blood vessels in the deep dermis and subcutaneous tissue. The mediators such as histamine cause vasodilation, increased permeability, and exudate from the blood vessels into the loose tissue to form localized edema. It is a common disease in dentistry. It is characterized by a sudden onset, but it is also rapid, and most patients have recurrent episodes. Certain drugs, such as aminoglycoside antibiotics, captopril, etc., may cause angioedema.

Cause

Cause:

It is due to a decrease in the level of C1 esterase inhibitor in blood and tissues, or inactivity. It is the involvement of small blood vessels in the deep dermis and subcutaneous tissue. The medium such as histamine causes vasodilation, increased permeability, and exudate forms a localized edema from the blood vessels into the loose tissue. Certain drugs, such as aminoglycoside antibiotics, captopril, etc., may cause angioedema.

an examination

Related inspection

Determination of Serum C1q Serum Complement C4 Serum Complement C4 Content by General Radiography

an examination:

It has the characteristics of paroxysmal, repetitive and non-depression. It is generally not itchy and can be single-shot. Suddenly, the swelling of normal skin color appears on the lips, side of the face or limbs, or due to severe swelling and compression of superficial capillaries. It is white swelling and damage, the edge is unclear, local tension is felt, and the general itching is not obvious. This kind of damage can naturally disappear within a few days, but it can happen again. Some patients can also have more than two lesions, generally no systemic symptoms. . A small number of patients can cause suffocation due to the occurrence of pharyngeal isthmus. Failure to do so can result in death.

Differential diagnosis

Symptoms of angioedema that are confusing:

The disease sometimes needs to be differentiated from other edema of the skin: such as contact dermatitis in the eyelids, which may resemble angioedema in the early stage, but soon there will be pleomorphic lesions such as papules, blisters and scars. Due to insect bites, acute wheal-like reactions caused by hedgehogs or secondary cellulitis, in addition to local swelling, there are symptoms such as redness, fever and tenderness for identification.

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