Erythematous nodules

Introduction The erythema erythema (EN) is a reactive inflammatory disease involving the dermal and lipid-membrane tissues. The anterior skin of the calf is red or purple-red nodular changes. Can be seen at any age, but it is more common in young and middle-aged women, more common in spring and autumn.

Cause

It is generally believed to be associated with infections, especially streptococcal infections and drug reactions. Favone and Sosman analyzed 155 cases of EN, and more than 80% of upper respiratory tract infections occurred before symptoms occurred, 50% of which were pharyngitis caused by p-hemolytic streptococcus. Tuberculosis is also an important predisposing factor, especially for children. In addition, viruses, fungi and other infections, bromide, iodide, sulfonamides and other drugs can also induce the disease. Recently, there have been reports of oral contraceptives. The disease may also appear as a concomitant symptom in certain diseases, such as sarcoidosis, leprosy, ulcerative colitis, localized enteritis, lymphoma, leukemia, Behcet's disease, connective tissue disease, and the like. The pathogenesis of EN is not fully understood. Some people think that it may be a delayed type of allergic reaction to certain pathogenic microbial antigens. Some people think that it is an immune complex disease.

an examination

Related inspection

Physical examination of skin diseases Skin color Skin elasticity examination Anti-polymyositis-1 Antibody skin cancer detection

High fever can last for days, weeks or months. Skin in any part of the body appears in different sizes of erythema-like subcutaneous nodules and plaques and pain. It subsides after a few weeks, but leaves depression and hyperpigmentation. A small amount of necrotic ulcers flow out of yellow liquid, and the whole body looks like a sore. Hundred holes. It also shows signs of visceral lesions caused by damage to visceral adipose tissue, such as abdominal pain, bloating, cytopenia, abnormal liver function, joint pain, and neurological diseases.

Differential diagnosis

1. Hard erythema: nodules often occur in the flexor of the calf, the pain is mild, easy to rupture, after a slow, histopathological changes of tuberculosis.

2. Regressive febrile nodular non-suppurative panniculitis: more common in the thigh, buttocks and trunk. The systemic symptoms are significant at the time of rash, and there is a regression of fever and a special histopathological image. Irrespective of the season, some patients with nodules can be necrotic and ruptured, oily fluids flow out, and recessed atrophy can be left after the nodules have subsided.

3. Nodular vasculitis: This disease occurs in middle-aged women. The nodules are mainly located on the lateral and posterior sides of the calf. After a slow, occasional rupture. Some people think that this disease is early or light in hard erythema. High fever can last for days, weeks or months. Skin in any part of the body appears in different sizes of erythema-like subcutaneous nodules and plaques and pain. It subsides after a few weeks, but leaves depression and hyperpigmentation. A small amount of necrotic ulcers flow out of yellow liquid, and the whole body looks like a sore. Hundred holes. It also shows signs of visceral lesions caused by damage to visceral adipose tissue, such as abdominal pain, bloating, cytopenia, abnormal liver function, joint pain, and neurological diseases.

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