5-hydroxyindoleacetic acid

About 5-1/2 of 5-HT is discharged after the liver is combined with sulfuric acid or glucuronic acid, or 吲哚 is broken and decomposed; about 1/3 of the landscape monoamine oxidase acts to oxidatively deamination to form 5-HIAA and is discharged from the urine. 5-HIAA is the final product of 5-hydroxytryptophan metabolism and is not biologically active. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Carcinoid tumor syndrome, food and medicine (banana, tomato, apricot, walnut, eggplant, reserpine, phenothiazine derivative, Lugol's solution). Tips: Avoid all kinds of drugs that may be affected. Stop taking the drug 1 to 2 days before the measurement to avoid interference. Normal value Qualitative (fresh urine) negative. Quantitative (urine) 10.5 ~ 42.0 μmol / 24h (2 ~ 8mg / 24h). Clinical significance Positive (or elevated) carcinoid syndrome, food and medicine (banana, tomato, apricot, walnut, eggplant, reserpine, phenothiazine derivative, Lugol's solution). Positive results may be diseases: appendix carcinoid, small intestine carcinoid, liver carcinoid precautions (1) After the specimen is collected, it should be measured immediately or stored in the refrigerator for freezing, but not more than 1 week. (2) Avoid all kinds of drugs that may be affected. The drug should be stopped 1 to 2 days before the measurement to avoid interference. Inspection process (1) Add 0.2 ml of fresh urine to the test tube, add 0.8 ml of water and 0.5 ml of 1-nitroso-2-naphthol solution to mix. (2) Another normal urine was taken as a negative control, and the added reagent was the same as above. (3) Add 0.5 ml of new nitrous acid reagent to each tube and mix. (4) After each tube was allowed to stand at room temperature for 10 min, 5 ml of dichloroethylene (or ethyl acetate) was added, and shaken, and if it was cloudy, it was centrifuged. (5) The upper liquid purple is positive. The normal control was light yellow (<41.8 μmol/d or <8 mg/d). More than 5 times higher than normal human 5-HI-AA, purple is obvious. Not suitable for the crowd No taboos. Adverse reactions and risks No.

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