Serum Immunoprotein Electrophoresis

Immunoglobulin is a kind of antibody-containing globulin, which is the material basis and execution unit of the body-specific humoral immune response. Its main function is to react with invading pathogenic microorganisms (conditioning, neutralization, braking, promoting phagocytosis or cytolytic reaction), protect the body from pathogens; remove self-antigenic substances, participate in immune regulation, and maintain the body The internal environment is stable. Under the action of an external DC power source, the colloidal particles move in a direction toward the cathode or the anode in a dispersion medium. This phenomenon is called electrophoresis. Separation of substances by electrophoresis is also called electrophoresis. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: The specimen should be fresh venous blood, and the specimen should not be hemolyzed. Normal value Cellulose acetate membrane method Clear protein 0.57 ~ 0.68; 11 globulin 0.01 to 0.06; 22 globulin 0.06 ~ 0.10; Beta globulin 0.07 ~ 0.15; Gamma globulin 0.10 to 0.20. Clinical significance (1) M-proteinemia 1 malignant M-proteinemia multiple myeloma, Waldenstron's syndrome (Walton Strom's giant globulin, primary macroglobulinemia) and so on. 2 primary M-proteinemia. 3 incomplete molecular M-type proteinemia heavy chain disease, semi-molecular myeloma and the like. (2) no (low) proteinemia immunodeficiency syndrome, no (low) globulinemia, no hemoglobinemia, no transferrinemia, no fibrinemia, ceruloplasmin deficiency , congenital lipoprotein deficiency, C3 deficiency. (3) Other acute inflammation, chronic inflammation, cirrhosis, nephrotic syndrome, amyloidosis, cryoprecipitate globulinemia, and the like. Precautions (1) The specimen to be sent should be fresh venous blood, and the specimen cannot be hemolyzed. (2) Physiological elevation may occur in the following cases: α1 globulin elevation is seen after 6 months of pregnancy; α2 globulin elevation is seen in infants 1 to 6 months after birth, 4 to 6 months of pregnancy is moderately elevated, 7~ 9 months significantly increased; elevated beta globulin was found in infants after birth, 4 to 6 months of pregnancy; gamma globulin increased in the vaccination immunization vaccine. Inspection process Serum protein acetate membrane electrophoresis. Not suitable for the crowd There are no special taboos. Adverse reactions and risks No relevant information.

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