Activated protein C resistance test

The activated protein C resistance test (APCR) is a measure of the phenomenon in plasma. The extension of APTT was detected to judge the blood protein to undergo C resistance. Through in-depth research, it is found that APCD has congenital and acquired points. The former is mostly caused by hereditary defects of coagulation factors, the most common being factor VLeiden mutation. Under normal conditions, APC cleaves factor Va at Arg506, causing the latter to lose procoagulant activity. Symptoms can be relieved after thrombosis. Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: Take an empty stomach before check, pay attention to rest. Normal value APCR ratio = APC-APTT (S) / APTT (S) > 2.0. Clinical significance Abnormal result The activated protein C resistance test (APCR) was less than normal, and the APTT of the tested plasma was not prolonged, suggesting that there was a phenomenon of activated protein C resistance, which was closely related to the FVLeiden mutation. May have a blood clot. People who need to be checked There are people who are weak and weak, sleepy, pale skin, mucous membranes, palpitations, dizziness, headache, tinnitus, vertigo, inattention, and lethargy. Low results may be diseases: portal vein thrombosis, thrombosis considerations Taboo before check: pay attention to rest. Blood is taken on an empty stomach. Requirements for inspection: No special requirements. Inspection process The FXII activator and partial thromboplastin are added to the test plasma to initiate the coagulation pathway and then the activated protein C (APC) is added. Determination of APTT prolongation is not obvious. Not suitable for the crowd Pregnant women, newborns. Adverse reactions and risks Risk of infection: If you use an unclean needle, you may be at risk of infection.

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