Serum total lipids

Serum total lipids are a general term for various lipid components of serum. Total lipids are determined by various methods such as weighing, colorimetry and turbidimetry. The weighing method is accurate, not only for serum total lipid determination, but also for total lipid determination of tissue homogenate, food and feces, but this method is more time consuming. Turbidimetry is simple, but the accuracy is poor. The colorimetric method is simple and accurate, and is suitable for clinical general requirements. Although serum total lipid determination is not routinely tested, it is a routine test for clinical patients such as intravenous hypertrophic therapy. Due to the complexity of the lipid components in the blood, the functions of the components are different, and the laws of changes in the blood are different. The lipid components in the disease are increased or decreased. Even if the lipid metabolism has obvious obstacles, the total lipid content can still be unchanged. The clinical significance of the change in total lipid content is not clear. Now, the blood lipid components can be measured separately, and serum total lipids have been measured less frequently. Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: Try to reduce the amount of exercise before blood draw, do not eat food, keep fasting, you can drink a small amount of water, in addition to some drugs that must be taken on time, try to take other drugs to the blood and then take it, so as not to some experiments The result is interference. Normal value 5 ~ 8g / L. Clinical significance The main serum lipids are total cholesterol (TC) and triglyceride (TG), and the increase or decrease of serum TC and/or TG can affect the total lipid content. Physiological increase was seen in eating fatty foods, which began to rise 2 hours after eating, reached a peak at 6 hours, and returned to normal after 14 hours. Pathological increase is seen in various causes of hyperlipidemia, diabetes, hypothyroidism, glycogen storage disease, chronic nephritis, nephrotic syndrome, atherosclerosis and so on. Reduced in severe liver disease, hyperthyroidism, cachexia and malabsorption syndrome. High results may be diseases: hyperthyroidism, nephrotic syndrome precautions (1) At this stage, one-step enzymatic method and two-step enzymatic method are allowed to coexist, and a gradual transition to a unified two-step method is required. Before the unification method, the laboratory should report “de-FG value” or “no FG value” when reporting the TG measurement result, which will help the clinician to correctly judge the result. (2) The average serum TG concentration in normal people is about 0.11mmol/L (10mg/dl). For the TG with large fluctuation range, the error caused by this is negligible, but the TG in this specimen is obviously increased. Affect the judgment of TG levels, such as diabetes, emotional stress, glycerol-containing drugs, intravenous nutrition, and glycerol contamination when taking blood samples. In addition, improper storage and handling of the specimen will result in hydrolysis of TG to produce TG. (3) Although there are not many specimens with high endogenous TG, in order to avoid possible errors, the recommendations in foreign literature are available for reference: clinical laboratories should have reagents that can be used to remove TG blanks, if necessary, for physical examination; Patients in outpatients may not have TG blanks, except for diabetes or other special clinics; TG>2.3mmol/L is best for TG blank correction. For some suspicious situations, such as high TG and serum opacity, the possibility of high TG should be ruled out. . Inspection process Subjects were venously collected and assayed in time for serum separation. Colorimetric determination. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.

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