Atrial natriuretic peptide (ANP)

Atrial natriuretic peptide is an active polypeptide synthesized, stored and secreted by the atrium, also known as atrial natriuretic factor (ANF) or atrial natriuretic peptide (ANP). Has a strong sodium, diuretic, diastolic blood vessels, lower blood pressure and anti-renin-angiotensin system and antidiuretic effects. The activity of serum ANP is measured for the diagnosis and monitoring of the course and efficacy of patients with heart failure. Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: More common in hyperthyroidism, atrial fibrillation. Normal value: RIA method: 0.145-0.95μg/L Above normal: More common in primary hypertension, coronary heart disease, heart failure and other diseases. negative: Positive: Reminder: Sample collection should be carried out under the same conditions as possible. For example, the same time every day, blood is collected after lying for 15 minutes on the back, so that the results are comparable. Normal value RIA method: 0.145 to 0.95 μg / L. Plasma: 0.11 to 0.60 nmol/L. Clinical significance Since atrial expansion is the main cause of AVP release, the concentration of ANP is closely related to left atrial pressure and pulmonary systolic pressure. 1, elevated in primary hypertension, coronary heart disease, heart failure, supraventricular tachycardia, premature cirrhosis, bronchial asthma, chronic obstructive pulmonary disease, aldosteronism, kidney disease. In acute myocardial infarction, elevated ANP on left ventricular dysfunction and AMI mortality are uniquely predictive, and elevated ANP concentrations in patients with acute myocardial infarction suggest poor long-term prognosis. 2, reduced in hyperthyroidism, atrial fibrillation. Low results may be diseases: Hyperthyroidism results may be high. Possible diseases: essential hypertension, heart failure, coronary heart disease considerations 1. Sample collection should be carried out under the same conditions as possible. For example, the same time every day, blood is collected after lying for 15 minutes on the back, so that the results are comparable. 2. Excessive activity and tachycardia will increase ANP. 3, should be excluded from liver and kidney disease, ANP in the liver and kidney disease will be due to the retention of people. Inspection process Subjects were venously collected and assayed in time for serum separation. It is determined by immunoturbidimetry, enzymatic method, and selective inhibition method. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.