glycoside-chenodeoxycholic acid

The bile acid synthesized by hepatocytes using cholesterol as raw material is called primary free bile acid. The primary free bile acid has two kinds of bile acid (CA) and chenodeoxycholic acid (CDCA), and its content change is of great value for diagnosing liver disease. In human liver cells, bile acids synthesized directly from cholesterol are called primary bile acids, including chenodeoxycholic acid. Gandodeoxycholic acid is a change from cholesterol in hepatocytes. It is one of the total bile acids. It is a bisulfonic acid derivative of 24 carbon atoms, which contains two hydroxyl groups (3α, 7α). The conversion process is complicated. It needs to be completed by a multi-step enzyme. Basic Information Specialist classification: Digestive examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: No clinical significance. Normal value: Glycoside-chenodeoxycholic acid (RIA method): 0.46-5.9 nmol/ml Above normal: Acute hepatitis, chronic hepatitis. negative: Positive: Tips: Determination of the ratio of glycosidic acid to glycosidic acid may have diagnostic value. Normal value The RIA method was 0.46 to 5.9 nmol/ml, and the CG:CDCG was 0.34 to 1.22. Clinical significance 1. Increase acute hepatitis and chronic hepatitis. 2, CG: CDCG <1 poor prognosis. 3, CG: CDCG> 1 prognosis is good. High results may be diseases: acute and chronic hepatitis precautions Determining the ratio of glycosidic acid to glycodeoxycholic acid may have diagnostic value because about 80% of patients with hepatocellular disease have a ratio of <1, while in 80% of patients with cholestasis disease the ratio is >1. Inspection process Determined by the principle of RIA. Not suitable for the crowd no. Adverse reactions and risks no.

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