triglycerides

Triglycerides are esters composed of glycerol and fatty acids. The glycerol fraction of each triglyceride is the same, and the fatty acid moieties may be the same or different. Increased in coronary heart disease, myocardial sclerosis, atherosclerosis, hypertension, diabetes, nephrotic syndrome. More than 2.26 mmol / liter is increased, called hypertriglyceridemia. Obese people tend to have higher triglycerides. Basic Information Specialist classification: cardiovascular examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: In the last meal before blood draw, avoid high-fat food and drinking, fasting 12 hours, extract forearm venous blood. Normal value According to the results of serum total cholesterol, triglyceride and high-density lipoprotein-cholesterol, hyperlipidemia is usually divided into the following four types: 1. Hypercholesterolemia: The serum total cholesterol content is increased, exceeding 5.72 mmol/L, and the triglyceride content is normal, that is, triglyceride <1.70 mmol/L. 2, hypertriglyceridemia: serum triglyceride content increased, more than 1.70 mmol / liter, and total cholesterol content is normal, that is, total cholesterol < 5.72 mmol / liter. 3. Mixed hyperlipidemia: serum total cholesterol and triglyceride levels are increased, that is, total cholesterol exceeds 5.72 mmol/L, and triglyceride exceeds 1.70 mmol/L. 4, low high density lipoproteinemia: serum high density lipoprotein-cholesterol (HDL-cholesterol) content decreased, <0.9 mmol / liter. Clinical significance Abnormal result Increase: seen in coronary heart disease, myocardial sclerosis, atherosclerosis, hypertension, diabetes, nephrotic syndrome. More than 2.26 mmol / liter is increased, called hypertriglyceridemia. Obese people tend to have higher triglycerides. Reduction: common in hyperthyroidism, adrenal insufficiency, liver parenchymal disease, chronic obstructive pulmonary disease, cerebral infarction, cachexia, primary low-density lipoprotein (β-lipoprotein) deficiency, and dyspepsia. Need to check the crowd Regular inspections are recommended to be carried out on a regular basis. Low results may be diseases: high alcoholic fatty liver results may be diseases: hyperlipoproteinemia type III, hyperlipoproteinemia type II, hyperlipoproteinemia type IV, hyperlipidemia, hyperlipoproteinemia V-type, hyperlipoproteinemia type I, progressive lipodystrophy, arteriosclerosis, obesity, diabetic ketoacidosis precautions Preparation before inspection: In the last meal before blood draw, avoid high-fat food and drinking, and fasting for 12 hours, extract forearm venous blood. Note when checking: If you find any discomfort during blood draw, you should inform the doctor promptly. Not suitable for people: Nothing is suitable for the crowd. Inspection process The method of measuring serum TG can be generally divided into three major categories: chemical method, enzymatic method and chromatography method. Early assays were estimated by the difference between total lipids and cholesterol and phospholipids. The chemical method extracts the TG in the sample with an organic solvent, removes the interference product such as phospholipids in the extract, and then hydrolyzes (saponifies) TG with an alkali, oxidizes glycerol with periodic acid to form formaldehyde, and then measures formaldehyde by a color reaction. More accurate is the methylene chloride-silicic acid-chromic acid method (VanHandel-Caslson method), this method extracts completely, can remove phospholipids and glycerol interference, chromotropic acid color development sensitivity, color stability, and still is the US disease control Internal Reference Method with the Prevention Center (CDC). However, due to the numerous operational steps and high technical requirements, it is not suitable for routine work applications. Nuclide dilution/gas chromatography/mass spectrometry (ID/GC/MS) is mainly used as the definitive method in the reference system and the preparation and determination of reference materials. This method is expensive, the sample processing is complicated, and it is difficult to popularize and apply. Not suitable for the crowd There are no taboos. Adverse reactions and risks There is no obvious concurrent performance.

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