Β2-microglobulin clearance test

β2-microglobulin clearance test is an auxiliary test method used to check whether the urination function is normal. β2-microglobulin is a small molecular protein with a molecular weight of 11,800. β2-microglobulin (β2-MG) is produced by lymphocytes, platelets, and polymorphonuclear leukocytes. Tumor cells have a strong ability to synthesize β2-microglobulin. . Β2-microglobulin that enters the blood circulation can be freely filtered from the glomerulus, about 99.9% is reabsorbed by the proximal tubule, and only 0.1% is excreted from the final urine. When β2-microglobulin synthesis increases in the body or renal excretion decreases Can cause blood β2-microglobulin to increase, so β2-microglobulin is a sensitive indicator for evaluating renal function, and is also an important indicator in tumor diagnosis and differential diagnosis.

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