Antithyroid peroxidase antibody

Thyroid peroxidase is the main antigen component of thyroid microsomes, and its function is related to the synthesis of thyroxine. Antithyroid peroxidase antibodies or antithyroid microsomal antibodies may damage thyroid cells. The method for detecting anti-thyroid peroxidase antibodies is similar to that for anti-thyroglobulin antibodies. The clinical significance of measuring anti-thyroid peroxidase antibodies is similar to that of anti-thyroglobulin antibodies. It is mainly useful for chronic lymphocytic thyroiditis, hyperthyroidism, and primary hypothyroidism. . Some patients are negative for antithyroglobulin antibodies, but antithyroid peroxidase antibodies are positive, so simultaneous detection of both antibodies can increase the positive detection rate of antithyroid autoantibodies, and can be used for clinical diagnosis and differential diagnosis of autoimmune thyroid An important basis for inflammation.

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