Serum blocking antibody

In the serum of normal pregnant women, there is a specific IgG antibody against spouse lymphocytes, which can inhibit lymphocyte response (MLR), block the cytotoxic effect of maternal lymphocytes on the cultured trophoblast, and prevent helper T cells from recognizing the fetus. An inhibitor of the antigen and can prevent the mother's immune system from attacking the embryo. Blocking alloantigen-stimulated lymphocytes produces macrophage migration inhibitory factor (MIF), so it is called blocking antibodies (BA). Blocked antibody test is to check whether the serum of pregnant women contains such antibodies.

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