Pediatric hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a hereditary disease characterized by ventricular hypertrophy and no enlargement of the heart cavity. HCM is also known as idiopathic subaortic stenosis (ISS) and Asym-metric septal hypertrophy (ASH). Diverse clinical manifestations are one of the causes of sudden death in older children and adolescents. Pediatric hypertrophic cardiomyopathy includes a group of diseases of different etiology, which is characterized by abnormal and unexplained ventricular hypertrophy without enlargement of the heart cavity, mainly left heart involvement, right ventricular myocardium can also be affected, and ventricular hypertrophy is asymmetric and unbalanced. It is uniform, the ventricular cavity becomes smaller, and the left ventricular blood is blocked and the left ventricular diastolic compliance is reduced to a basic pathological state. Histologically, a group of myocardial diseases with disordered myocardial fiber arrangement. HCM was first described by Liouville and Hallopeau in 1869. In November 2003, the American College of Cardiology / European Society of Cardiology and the American Heart Association agreed on three types of HCM: ① pressure difference of 30mmHg during obstructive-quiet time; ② pressure grade during obstructive-load exercise The difference is 30mmHg; ③ non-obstructive-quiet and pressure step difference after loading are 30mmHg.

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