Serum free protein S

Free S protein measurement is to diagnose the disease by measuring the content of free S protein in the human body. Free S protein is an alpha single-chain glycoprotein in serum with a molecular weight of 83 kDa. The main regulatory effect of SP is to compete with the metastable binding site of C5b-7 for target cell membrane lipids. By forming a hydrophilic SPC5b-7 (abbreviated as S5b-7) complex, C5b-7 will lose membrane binding active. This protects cells adjacent to the site of complement activation from accidental attack.

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