Diffuse flushing all over the body

Introduction Diffuse flushing of the whole body refers to a type of symptom characterized by flushing and edema of multiple skin parts of the body. Diffuse flushing is one of the typical symptoms of erythroderma.

Cause

Common causes are: tumor, lymphoma or leukemia patients; psoriasis, eczema, hair red pityriasis and so on.

an examination

Related inspection

Blood routine immunopathological examination plasma protein S determination antigen intradermal test

Typical manifestations are diffuse flushing, infiltration, swelling, and scaling of the skin. The affected area of the skin lesions reaches more than 80% of the entire skin. In addition, many complications can occur. Common ones are:

(1) Mucosa: Symptoms are more obvious, and there may be ocular conjunctivitis, orbital blepharitis, keratitis, corneal ulcer, oral redness, ulcers, pain, and worsening symptoms when swallowing. The mucous membranes of the female genitals, urethra and anus are often eroded and have secretions.

(2) Skin appendage: hair loss, light hair sparse, heavy can cause a large number of shedding. The more severe the condition, the more obvious the hair loss, and the hair can be regenerated after the condition is restored. A nail can appear atrophy, turbidity, depression, etc., especially the most obvious change caused by psoriasis.

(3) lymphadenopathy: 2/3 patients have different degrees of lymphadenopathy, of which the groin and axillary lymph nodes are the most affected, followed by the neck.

Differential diagnosis

Clinically often identified with lupus erythematosus.

Lupus erythematosus is an autoimmune disease with slow onset, insidious attack, diverse clinical manifestations, and a variety of autoimmune diseases involving many systems and organs. It produces a variety of autoantibodies due to cellular and humoral immune dysfunction. . It can affect the skin, serosa, joints, kidneys and central nervous system, and is characterized by autoimmunity. There are many autoantibodies in patients, which not only affects humoral immunity, but also affects cellular immunity, and the complement system also changes. The pathogenesis is mainly due to the formation of immune complexes. The exact cause is unknown. The condition is an alternating process of recurrent and remission. The disease is more common in young women. The prevalence rate in China is higher than in Western countries and may be related to genetic factors.

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