Greyish-white hair

Introduction Congenital systemic white onset is associated with albinism, body hair is grayish white, skin and iris are lack of pigment. Hereditary white hair is usually present at birth or rapidly during childhood. It includes albinism with whitening of systemic hair and mottled disease with localized whitening of hair. Canments Senilis, whose white hair often starts from the two corners and develops chronically to the top of the head. After a few years, the beard and nose hair are also grayish, but the chest hair, pubic hair and mane are not white even in old age.

Cause

(1) Causes of the disease

Senile white hair is a physiological phenomenon. White onset can be divided into congenital and acquired. Congenital white hair is associated with albinism at the same time, and sometimes occurs in some patients with hereditary diseases, such as ataxia-telangiectasia syndrome and Rothmund syndrome. Except for senile white hair, it is more common in white hair. It may be related to heredity, but trauma, emotional agitation, pessimistic depression, malnutrition, etc. are also important factors. Sometimes it is one of the symptoms of certain diseases, such as common adrenal insufficiency, Vogt-Kayanagi syndrome, Alezzandrini syndrome.

(two) pathogenesis

The melanocyte tyrosinase activity in the hair bulb is progressively lost, and the pigment in the hair shaft gradually disappears. The number of melanocytes in the gray hair is normal, but there are large vacuoles in the cytoplasm, and the pigment contained in the melanin bodies is reduced; while the melanocytes in the white hair are reduced or lacked.

an examination

Related inspection

blood test

According to the clinical manifestations, the characteristics of all or part of the whitening of the hair can be diagnosed. White hair is a disease, Chinese medicine has long been recorded, such as "the source of the disease" white hair waiting to describe: "The foot of Shaoyin is also the kidney, the bone marrow of the kidney, its Hua is hair. If the blood is strong, then the kidney is strong, kidney gas Strong, the bone marrow is full, so it is dark and black; if the blood is qi, the kidney is weak, the kidney is weak, then the bone marrow is exhausted, so it turns white."

Differential diagnosis

Clinically, it can be divided into the following categories:

Congenital systemic white onset

Accompanied by albinism, the whole body hair is grayish white, and the skin and iris are lack of pigment.

2. Congenital localized white disease

There is a family history, there are 1 or several localized white hair areas in some parts of the body, sometimes the eyebrows and eyelashes are white. If the hair is a ring-shaped pigment, it is called leukotrichia annularis.

3. Senile white hair

It is a kind of performance of aging. Generally, after 40 years old, it starts up in two, and gradually the hair can be whitened.

4. Adolescent white disease

Common in adolescents, also known as premature white onset.

Initially, the hair is sparsely scattered in a small amount of white hair, which can gradually or suddenly increase. Suddenly, it may be related to nutritional disorders.

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