Red or purple, slightly raised papules or nodules

Introduction Skin leukemia lesions are papules or nodules that are slightly elevated in red or purple; patients with skin fibrosis may also have papules or nodules that are slightly elevated in red or purple. Skin leukemia is a malignant tumor of white blood cells in the blood. It is characterized by immature white blood cells diffusely infiltrating the bone marrow and an abnormal number of immature white blood cells in the blood. In addition, immature white blood cells often infiltrate the liver and spleen lymph nodes and other organs including the skin. Skin myelofibrosis, also known as extramedullary hematopoiesis, is a chronic myeloproliferative disorder.

Cause

(1) Causes of the disease: The cause is still unknown.

(B) pathogenesis: the pathogenesis is still unclear.

Skin leukemia is a malignant tumor of white blood cells in the blood. It is characterized by immature white blood cells diffusely infiltrating the bone marrow and an abnormal number of immature white blood cells in the blood. In addition, immature white blood cells often infiltrate the liver and spleen lymph nodes and other organs including the skin.

Skin myelofibrosis, also known as extramedullary hematopoiesis, is a chronic myeloproliferative disorder.

an examination

Skin leukemia

The lesions are papules or nodules that are slightly elevated in red or purple. In some cases, the papules can be fused into plaque-like lesions that can cause hemorrhagic lesions, and continue to enlarge to form ulcer lesions, which are widely distributed. The most commonly affected parts are the limbs and neck of the trunk, but there are also single large nodules or plaques. There are also reports of hemorrhagic lesions of the bullae and painful genital ulcers. For example, the origin of the AMT is about 2%~ 4% of patients develop leukemia gingivitis, chronic myeloid leukemia (CML)-specific damage is rarely reported to be 2% to 8%, and juvenile CML is a rare childhood malignant tumor characterized by rapid progression of the disease. Round red ring plaques and nodules are found in a small number of juvenile CML green tumors or granulosa cell sarcomas, which are rare in AML or CML. The clinical manifestations usually damage single hair, and occasionally multiple lesions are red reddish brown or yellowish green. Nodules or plaques.

2. Skin myelofibrosis

Newborns can see hemorrhagic purpura and blueberry muffin syndrome. Hemorrhagic purpura is characterized by a small reddish rash in the palm of the newborn without special clinical disease. The rash is a residual damage to the growth of physiological dermal red blood cells during embryonic development. A slightly elevated purplish red or dark blue papule that occurs during the birth of a newborn in the purple-blackberry muffin syndrome usually resolves within 4 to 6 weeks. Adult skin lesions are scattered asymptomatic maroon or purple hemorrhagic papules, nodules or small plaques. Most often occurs in the abdomen of older men. Liver, spleen and lymph nodes often swell, which is caused by extramedullary hematopoiesis in these organs. According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

Differential diagnosis

Differential diagnosis

1, miliary papules: miliary papules can be caused by a variety of causes, is a concomitant symptom of a variety of diseases. It is called white acne or millet rash white moss. A benign mass or a retention cyst that originates in the epidermis of the epidermis or appendage. Can occur at any age, gender, and also in newborns. Mildew rashes caused by trauma often occur after bruising, scratching, or facial inflammatory rash. Common in skin lesions of porphyria or bullous epidermolysis, it can also occur after blisters of blisters, and some patients have genetic factors. Acne is a skin disease that occurs when oily, dead epidermal cells block your pores. Some people call it blackheads, miliary rashes, or pimples. Facial miliary lupus, a round, unbroken pimples scattered around the face, with atrophic scars remaining.

2, maculopapular rash: a red skin around the papules called the maculopapular rash.

3, crimson papules: Kaposi sarcoma skin damage is red, purple red, light blue black, crimson papules or plaques, gradually increased into a large plaque, nodules, nodules as hard as rubber.

diagnosis

Skin leukemia

In some cases, the papules or nodules are slightly elevated in red or purple. In some cases, the papules can be fused into plaques. Hemorrhagic lesions can occur. The nodules continue to enlarge. The ulcers can be formed. The most common sites are the trunks and the neck. However, there are also cases of single large nodules or plaques. Reporting of bullous hemorrhagic lesions and painful genital ulcers such as AMT. About 2% to 4% of patients with leukemia gingivitis have chronic myeloid leukemia ( CML) Specific damage is rare. The reported incidence is 2% to 8%. Young CML is a rare childhood malignant tumor characterized by rapid progression of disease. Circular red annular plaques and nodules are found in a small number of juvenile CML green tumors. Granulocyte sarcoma is a rare clinical manifestation of AML or CML that usually impairs a single hair couple or multiple lesions with reddish-brown or yellowish green nodules or plaques.

2. Skin myelofibrosis

Newborns can see hemorrhagic purpura and blueberry muffin syndrome. Hemorrhagic purpura is characterized by a small reddish rash in the palm of the newborn without special clinical disease. The rash is a residual damage to the growth of physiological dermal red blood cells during embryonic development. A slightly elevated purplish red or dark blue papule that occurs during the birth of a newborn in the purple-blackberry muffin syndrome usually resolves within 4 to 6 weeks. Adult skin lesions are scattered asymptomatic maroon or purple hemorrhagic papules, nodules or small plaques. Most often occurs in the abdomen of older men. Liver, spleen and lymph nodes often swell, which is caused by extramedullary hematopoiesis in these organs. According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.