Intraosseous damage

Introduction

Introduction Microcirculatory disorders (ischemia, congestion, disseminated intravascular coagulation) cause microcirculatory arterial blood perfusion, and bone function and metabolic disorders due to hypoxia. Mainly manifested as microvascular endothelial injury and microthrombus formation. The blood vessels of the human body are the pipes that transport blood. It is like a big river, gradually branching and irrigating the surrounding land. It is also nurturing tissue cells around the blood vessels. As the blood passes through the large blood vessels to the tiny arterioles, it flows through the widely distributed capillary network and then merges into the tiny venules. Because this part of the blood vessel has a small caliber, it is invisible to the naked eye and can only be seen under a microscope, so it is called a microcirculation.

Cause

Cause

Ultrastructural damage and thrombosis of the surface of microvascular endothelium in osteonecrosis caused by hormone combined with endotoxin.

Examine

an examination

Related inspection

Bone and joint plains of the extremities, bone marrow hyperplasia, bone and joint MRI, bone mineral density

The surface of the subchondral microvascular endothelium is uneven, and the lumen is irregular, showing lumen filling and thrombosis.

Diagnosis

Differential diagnosis

The symptoms of intraosseous damage need to be identified as follows.

(1) Microcirculation ischemic period (ischemic hypoxia)

The characteristics of this microcirculation change are: 1 micro-arterial, posterior micro-arterial and capillary sphincter contraction, microcirculation perfusion flow decreased sharply, pressure decreased; 2 venules and venules were less sensitive to catecholamines, and contraction was lighter; 3 arteriovenous anastomosis may have different degrees of openness, blood from the arterioles through the arteriovenous anastomosis directly into the venules.

(2) Microcirculation and congestion period (congestive anoxic period)

(C) microcirculation coagulation period (distributed intravascular coagulation)

The surface of the subchondral microvascular endothelium is uneven, and the lumen is irregular, showing lumen filling and thrombosis.

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