Oral focal epithelial hyperplasia

Introduction to oral focal epithelial hyperplasia The disease was first reported by Heck in 1961 and named by Archhard in 1965. It is characterized by multiple high-level sputum lesions in the oral mucosa, mainly in the Eskimos in India, North America, South America and Greenland. It is often localized in a small area, and individual reports have family tendencies. basic knowledge The proportion of illness: 0.003% Susceptible people: more common in children Mode of infection: non-infectious complication:

Oral focal epithelial hyperplasia

(1) Causes of the disease

Some scholars have found nuclear particles in the lesions, the size and shape of which are consistent with HPV, and some people have determined that the virus is HPV-1, but some people think that it is related to heredity, and the occurrence of this disease has been confirmed and HPV-13, 32 related.

(two) pathogenesis

It has been determined that the occurrence of this disease is related to HPV-13,32, and this virus only infects the mouth. The virus that infects the vagina and skin can also infect the mouth. HPV-6,11,16 has also been found in oral cavity-like lesions.

Prevention of oral focal epithelial hyperplasia

There is no effective preventive measure for this disease. Early detection and early diagnosis are the key to the prevention and treatment of this disease.

Oral focal epithelial hyperplasia complications Complication

There is no complication of this disease.

Oral focal epithelial hyperplasia symptoms common symptoms nodular itching nodular nodules papules grow slowly

More common in children, the mouth can be seen in multiple, soft, white, scattered papules, nodules and sputum-like damage, diameter 2 ~ 4mm, rash can also fuse with each other, occurs in the lips, tongue, gums and cheeks, chronic disease , often can be naturally relieved.

Examination of oral focal epithelial hyperplasia

Histopathological examination: thickening and prolongation of the epidermis, the vacuolar cells of the epithelium are scattered and stained in the whole epithelium. The vacuolar cells are obvious in the upper part of the epidermis, but can also be extended to the widening. In the epidermis, the basal cell layer is free of vacuoles, some vacuoles are formed, and some vacuolated cells are seen as binuclear.

Diagnosis and differentiation of oral focal epithelial hyperplasia

According to its multiple fusion of papular lesions, the location of the site and the characteristics of chronic progression, the diagnosis is not difficult.

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