Mycobacterium zurgai infection

Introduction to Mycobacterium sulcata infection Mycobacterium szulgai was confirmed to be a human pathogenic bacterium by Marks in 1972. It belongs to the genus Mycobacterium sphaeroides. It is cultured at 25 ° C for light production, cultured at 37 ° C for dark color, and does not grow at 42 ° C. The colonies are orange and grow slowly. The pathogenesis is still not clear, and the clinical manifestations are diverse. Skin lesions are disseminated painless inflammatory nodules, and the lesions can be diagnosed by positive mycobacterial culture. The combination of ethionamide, isoniazid and rifampicin is effective. basic knowledge The proportion of illness: 0.002% Susceptible people: no specific people Mode of infection: non-infectious complication:

Causes of Mycobacterium sulcata infection

(1) Causes of the disease

Mycobacterium szulgai was confirmed to be a human pathogen by Marks in 1972. It belongs to the genus Mycobacterium sphaeroides. It is cultured at 25 °C for light gas production, cultured at 37 °C for dark color, and does not grow at 42 °C. The colonies are orange and grow slowly. The optimum growth temperature is 22-33 °C. Colonies form from 10 weeks to 9 months. The enzymes are strong, the nitrate enzyme and urease test are positive, and the Tween hydrolysis reaction is delayed.

(two) pathogenesis

The pathogenesis is still not very clear, and there is currently no relevant content description.

Prevention of Mycobacterium infection in Zurga

Prognosis: There is pigmentation after the healing, and scarring is rarely formed.

Complications of Mycobacterium sulcata infection Complication

Generally no special complications

Symptoms of Mycobacterium sulcata infection Common symptoms Skin atrophy and pigmentation Pulmonary infection nodules

More common in middle-aged men, clinical manifestations are diverse, lung infections resemble tuberculosis or interstitial pneumonia, skin lesions are disseminated painless inflammatory nodules, 2 ~ 4cm size, hard, occasionally ruptured, scattered Distributed in the trunk and limbs, the pigmentation is left behind, and scars are rarely formed.

According to the clinical manifestations and characteristics of skin lesions, histopathological examination; mycobacterial culture of skin lesions is positive, can be diagnosed.

Examination of Mycobacterium sulcata infection

Mycobacterium tuberculosis culture was positive.

Histopathology: The ulcerated nodule biopsy showed ulceration and granulation tissue in the dermis, lymphocytes around the blood vessels, infiltration of plasma cells and histiocytes, granuloma at the junction of the dermis and subcutaneous tissue, composed of tissue cells and multinucleated giant cells. There are lymphocytes and plasma cells around the circumference, and the mycobacteria of the lesions are cultured positive.

Diagnosis and identification of Mycobacterium sulcata infection

For clinically common mycobacteria, there are readily available DNA probes, including Mycobacterium tuberculosis complexes, birds, intracellular, Kansas, Gordon and other mycobacteria. The probe was labeled with acridinium ester, and the result was measured by a fluorophotometer. The experimental period was only 2 h, and the method was simple and easy. The defects have been as described above: not all mycobacteria have known specific probes, and the probes of the Mycobacterium tuberculosis complex cannot distinguish between human type, bovine type and BCG.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.