Urinary norepinephrine (NNM)

Norepinephrine, also known as norepinephrine, belongs to the class of catecholamines. It is mainly released by sympathetic nerve endings, and a small part is released by the adrenal medulla. Mainly acts on alpha receptors. It has a strong contraction of blood vessels, especially a strong contraction of skin, mucous membranes and renal blood vessels, which raises blood pressure. However, it has a weak expansion effect on the coronary arteries, and also has an excitatory effect on the cardiac β receptor, but is weaker than adrenaline. Basic Information Specialist classification: neurological examination classification: urine / renal function test Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Total adrenalectomy, malnutrition, familial autonomic dysfunction, cervical spinal cord cross-section. Normal value: Urine norepinephrine: 10-70μg/L Above normal: Neuroblastoma, pheochromocytoma, ganglioneuroma, progressive muscular dystrophy, myasthenia gravis, extensive burns. negative: Positive: Tips: Therefore, patients with suspected disease should measure VMA and CA at the same time, which can improve the detection rate. Normal value The reference value is 10 to 70 μg/L. Clinical significance (1) Elevation: neuroblastoma, pheochromocytoma, ganglioneuroma, progressive muscular dystrophy, myasthenia gravis, extensive burns. (2) reduction: total adrenalectomy, malnutrition, familial autonomic dysfunction, cervical spinal cord cross-section. Low results may be diseases: high malnutrition results may be diseases: pheochromocytoma considerations in children In some patients with pheochromocytoma and neuroblastoma, the basal level of VMA in the urine is low, even if the tumor is present, and the VMA level is still normal, or the VMA may be normal or only slightly higher than normal during the non-onset. Therefore, patients with suspected disease should measure VMA and CA at the same time, which can increase the detection rate. Inspection process As with conventional urine tests, use a clean, dry container, preferably a disposable urine cup and a urine test tube provided by the hospital. Take about 10 ml of urine and send it to the designated inspection window of the hospital for examination by a doctor. Not suitable for the crowd Menstrual women. Adverse reactions and risks no.

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