Urine prostaglandins

PG is a family of biologically active substances belonging to unsaturated fatty acids. It has many physiological functions and can act as an information regulating molecule. It can affect the development and growth of the body by regulating genetic information (RNA, DNA), neurotransmitters and hormone levels. Reproduction and a series of neuroendocrine effects. PG is widely found in many tissues and body fluids, with the highest concentration in semen. At present, more than 20 species have been found, which are classified into A, B, C, D, E, F, G, and H types according to their five-carbon ring structure. The four types of PGE, PGF, PGA, and PGB are the most important, and According to the number of double bonds contained in the side chain, it can be further divided into three kinds of compounds, such as E type, which can be divided into PGE1, PGE2, and PGE3. PGE1, PGE2, F1a, F2a, etc. are widely distributed in the brain, spinal cord, peripheral nerve and CSF, and the content of E2α is the most abundant. PGE2a is a cerebral vasoconstrictor, and the concentration of TGF2a in CSF is increased when cerebral vasospasm is observed. Basic Information Specialist Category: Inspection Category: Urine/Kidney Function Test Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Essential hypertension, atherosclerosis, angina pectoris, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, etc. Normal value: PGE: 366.5-612.5ng/24h PGF: 1033-2371ng/24h Above normal: Malignant tumors, pregnancy, hypoxemia, angina pectoris, childbirth, uremia, myocardial infarction, Barth's syndrome (hyperaldosteronism and hypokalemia syndrome), essential hypertension, Renal transplant rejection, nephrotic syndrome, diabetes, hyperlipidemia, etc. negative: Positive: Tips: Do not exercise vigorously, maintain a good diet and work. The middle part of the urine is taken for inspection. Women in the menstrual period, cold patients are not suitable for this examination. Normal value RIA method: PGE: 489.5 ± 123 ng / 24 h. PGF: 1702 ± 669 ng / 24 h. Clinical significance Abnormal result 1, elevated: malignant tumors, pregnancy, hypoxemia, angina pectoris, childbirth, uremia, myocardial infarction, Barth syndrome (hyperaldosteronism and hypokalemia, juxtaglomerular hyperplasia syndrome), the original Hypertension, renal transplant rejection, nephrotic syndrome, diabetes, hyperlipidemia, etc. 2, lower: essential hypertension, atherosclerosis, angina pectoris, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome. People who need to be tested People with angina pectoris, high blood pressure, kidney transplantation, and urine sugar. High results may be diseases: multiple pregnancy precautions Before the test: Do not exercise vigorously, maintain a good diet and rest. At the time of examination: a part of the urine is discharged first to wash away the bacteria remaining in the urethra and the anterior urethra, and then the middle part of the urine is taken for inspection. Not suitable for the crowd: women in the menstrual period, cold patients. Inspection process The urine of the subject was collected and detected by the RIA method. Not suitable for the crowd Women in the menstrual period, cold patients. Adverse reactions and risks no.

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