Plasma thyrotropin-releasing hormone (TRH)

Plasma thyroid stimulating hormone releasing hormone (TRH) is an indicator of hypothalamic function. When the plateau hypothyroidism is increased, both TRH and TSH are increased. In severe cases, the plasma TRH can reach 970 pmol/L. Secondary hypothyroidism, such as Xihan syndrome, increased TRH, decreased TSH, which is pituitary hypothyroidism. TRH and TSH, T3, and T4 all decreased, often hypothalamic hypothyroidism. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Found in congenital simple TRH deficiency. Hypothalamic dysfunction TRH decreased. Brain trauma can cause a decrease in hormone release from the hypothalamus and a decrease in TRH. Sedatives acting on the central nervous system, such as barbiturates, can inhibit hypothalamic secretion and reduce blood TRH; central nervous system stimulants can promote TRH release and increase blood TRH. Normal value: TRH: 14 pico / liter - 168 pico / liter TRH: 5 picograms / ml - 60 picograms / ml Above normal: When found in primary hypothyroidism, both TRH and TSH increased, and plasma TRH reached 970 pmol/l in severe cases. Secondary hypothyroidism, such as Xihan syndrome, increased TRH, decreased TSH, which is pituitary hypothyroidism. TRH and TSH, T3, and T4 all decreased, often hypothalamic hypothyroidism. Hyperthyroidism, TRH normal or decreased. Subacute thyroiditis, TRH is normal in early blood, and TRH is elevated in blood in the later stage of hypothyroidism. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. Normal value 14 to 168 pico/liter (5 to 60 picograms per milliliter). Clinical significance Clinical significance TRH is an indicator of hypothalamic function. Increased in primary hypothyroidism, TRH and TSH increased, plasma TRH in severe cases up to 970 pmol / liter. Secondary hypothyroidism, such as Xihan syndrome, increased TRH, decreased TSH, which is pituitary hypothyroidism. TRH and TSH, T3, and T4 all decreased, often hypothalamic hypothyroidism. Hyperthyroidism, TRH normal or decreased. Subacute thyroiditis, TRH is normal in early blood, and TRH is elevated in blood in the later stage of hypothyroidism. Reduced in congenital simple TRH deficiency. Hypothalamic dysfunction TRH decreased. Brain trauma can cause a decrease in hormone release from the hypothalamus and a decrease in TRH. Sedatives acting on the central nervous system, such as barbiturates, can inhibit hypothalamic secretion and reduce blood TRH; central nervous system stimulants can promote TRH release and increase blood TRH. High results may be diseases: congenital hypothyroidism in children, Sheehan syndrome, pediatric fibrous osteodystrophy syndrome, thyroid nodules First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. 3. Please inform the doctor about the recent medication and special physiological changes before the test. Inspection process Take appropriate amount of plasma and send it for inspection. Not suitable for the crowd People with reduced hematopoietic function such as leukemia, various anemia, myelodysplastic syndrome, or people with thrombocytopenia should pay attention to blood draw, and should not take more or more blood. Adverse reactions and risks 1. After the blood is drawn, do not press the needle hole to avoid subcutaneous hematoma. If there is a small piece of bruise in the blood, it is slightly tender, please don't panic, you can do hot compress after 24 hours to promote the absorption of blood. The general small amount of congestion will gradually absorb in 3 to 5 days and the color will become lighter and return to normal. 2. After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.

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