Sikh test

The Sikh test is an intradermal test that investigates whether a population has immunity to diphtheria. The principle is the neutralization of exotoxin and antitoxin. When the reaction was negative 24 to 48 hours after intradermal injection of toxin, it indicated that there was antitoxin in the body and immunity to diphtheria. Positive reactions such as redness and swelling of the skin indicate that there is no anti-toxin in the body and no immunity. In addition, the Sikh test can be used to check the immune effect after diphtheria vaccination. Basic Information Specialist classification: Infectious disease examination and classification: immunological examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: A negative reaction indicates immunity to diphtheria toxin. Positive: Positive indicates no immunity to diphtheria toxin. Tips: Disabled for people with severe illness, fever or a history of allergies. Normal value A negative reaction indicates immunity to diphtheria toxin; a positive indicates no immunity to diphtheria toxin. Clinical significance Abnormal results: local injection of this product after redness, induration, tenderness, itching, generally mild, systemic reactions such as low fever, lethargy, discomfort, vomiting, headache, shock and so on. People who need to be checked are not sure if they have immunity to diphtheria It is suitable for the positive diagnosis test before the injection of refined diphtheria toxoid in children and adults over 7 years old. In addition to measuring the body's susceptibility to diphtheria, this test can also detect whether immunity is produced after vaccination against diphtheria. Its essence is the in vivo neutralization reaction of toxins and antitoxins. Positive results may be diseases: diphtheria, pediatric X-linked agammaglobulinemia, pharyngeal diphtheria, diphtheria myocarditis, pediatric primary immunodeficiency disease considerations Taboo before the test: Can not have serious illness, temperature is too normal, people with a history of allergies. Requirements for inspection: If there is condensation, foreign matter, ampule cracking, product freezing, unclear label and expired, it cannot be used. A 1:1000 adrenaline should be available for emergency use when occasional shock occurs. Inspection process METHODS: A certain amount of diphtheria toxin was injected into the flexor of the forearm of the subject. Subjects with no immunity, 24-48 hours, local skin redness, positive in the diameter of 1 ~ 2 cm. On the contrary, if the subject is immune, the serum contains a sufficient amount of anti-toxin antibody, which can neutralize the injected toxin, and does not appear red and swollen locally, which is a negative reaction. Not suitable for the crowd Inappropriate people: those who are banned from serious illness, fever, or a history of allergies. Adverse reactions and risks It is a safe check and is harmless to the body.

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