Rabbit infection test

The rabbit infection test (RIT) is the most sensitive and reliable method for detecting Treponema pallidum, and RIT can confirm the existence of live Treponema pallidum. The rabbit infection test is a standard method commonly used to detect Treponema pallidum. However, routine diagnosis of neonatal or adult syphilis with RIT is not practical. Serological diagnosis of syphilis is significant for determining infection and treatment but is not sensitive to early diagnosis of syphilis. The diagnosis of congenital and neurosyphilis is not specific enough. Basic Information Specialist classification: Infectious disease examination and classification: immunological examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: The type and proportion of the flora in the body are normal, and the human body is in a state of dynamic balance and health. Positive: 1 stage syphilis. That is, hard chancre, with an incubation period of 2 to 4 weeks, a dark red hard mass, a shallow ulcer, a cartilage-like hardness, and a swollen peripheral lymph node. 2 second phase syphilis. After 1 to 2 months of primary syphilis, sympathetic rash, rash, pimples, pustular rash, etc. occur in the skin and mucous membranes of the whole body. Mucosal plaques, flat wet phlegm can occur in the mucosa, and the infection is strong. 3 third-phase syphilis. Occurred 2 to 3 years or even 10 years after infection, the skin is a gum-like swelling, and may also involve bone, joint, heart, blood vessels, manifesting aortic inflammation, aortic insufficiency and aortic aneurysm, etc., invading the nerve Spinal cord paralysis, general paralysis (paralytic dementia) and so on. Tips: Before the check: taboo: pay attention to normal eating habits, pay attention to personal hygiene. Unclean sexual intercourse is prohibited. Normal value The type and proportion of the flora in the body are normal, and the human body is in a state of dynamic balance and health. Clinical significance Abnormal results: 1 stage syphilis. That is, hard chancre, with an incubation period of 2 to 4 weeks, a dark red hard mass, a shallow ulcer, a cartilage-like hardness, and a swollen peripheral lymph node. 2 second phase syphilis. After 1 to 2 months of primary syphilis, sympathetic rash, rash, pimples, pustular rash, etc. occur in the skin and mucous membranes of the whole body. Mucosal plaques, flat wet phlegm can occur in the mucosa, and the infection is strong. 3 third-phase syphilis. Occurred 2 to 3 years or even 10 years after infection, the skin is a gum-like swelling, and may also involve bone, joint, heart, blood vessels, manifesting aortic inflammation, aortic insufficiency and aortic aneurysm, etc., invading the nerve Spinal cord paralysis, general paralysis (paralytic dementia) and so on. The person in need of examination has the above symptoms. Positive results may be diseases: secondary syphilis, third-stage syphilis, syphilis nephropathy precautions Forbidden before examination: Pay attention to normal eating habits and pay attention to personal hygiene. Unclean sexual intercourse is prohibited. Requirements for inspection: Actively cooperate with the doctor. Inspection process The serum of the patient to be examined is injected into the rabbit, and then the syphilis-causing syphilis spirochete is tested regularly. The rabbit infection test is a standard method commonly used to detect Treponema pallidum. However, routine diagnosis of neonatal or adult syphilis with RIT is not practical. Serological diagnosis of syphilis is significant for determining infection and treatment but is not sensitive to early diagnosis of syphilis. The diagnosis of congenital and neurosyphilis is not specific enough. Serological tests are used as an adjunct to congenital syphilis, and the primary problem is to distinguish asymptomatically infected infants from non-infected infants. The difficulty in the mother's syphilis serum test in these infants is that the mother's humoral immune response cannot be distinguished from the infant's antibody response because the mother's IgG can be passed on to the fetus. In addition, due to the lifetime existence of IgG, it is difficult to evaluate the treatment results. Serological diagnosis often has false positives. Not suitable for the crowd Inappropriate crowd: No. Adverse reactions and risks No harm to the body.

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