double-stranded enzyme intradermal test

The cellular immune skin test (referred to as the skin test) is a method for determining the immune function in the body. This method is simple and easy, and is of great significance for the diagnosis and prevention of allergic diseases, infectious diseases, immunodeficiency diseases and tumors. Negative (-): no redness, induration or induration diameter <5mm; positive (+): redness, induration diameter 5 ~ 14mm; strong yang (++) redness, induration > 15mm. Basic Information Specialist classification: Oncology examination classification: immune examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Negative (-) no redness, induration or induration diameter Positive: Positive (+) redness, induration diameter of 5 ~ 14mm; strong yang (++) redness, induration > 15mm. Tips: Keep your skin clean. Normal value Negative (-) no redness, induration or induration diameter <5mm; positive (+) redness, induration diameter 5 ~ 14mm; strong yang (++) redness, induration > 15mm. Clinical significance Basically the same as the OT test. OT" is tuberculin, OT test is to check whether the body has been infected by tuberculosis and produce immunity. After 4 to 8 weeks of infection with Mycobacterium tuberculosis, immune allergic reaction can be produced, tuberculin test (OT test) Is to use the body's allergic reaction to detect whether it has been infected with tuberculosis to help diagnose tuberculosis. OT test is now known as PPD test, PPD is human tuberculin pure egg self-derivative, the principle is the same OT test. Positive results may be diseases: anaphylactic shock, severe combined immunodeficiency disease, retinal tumor, small intestine tumor, combined immunodeficiency disease, breast cancer considerations It is of little significance to diagnose adult tuberculosis with this test. Inspection process The principle of double-stranded enzyme intradermal test: streptokinase and streptodornase are abbreviated as SK-SD, which are all enzymes secreted by streptococcus. The human body is often infected with streptococcus in life, and there are specific sensitized lymphocytes in the body. Therefore, the injection of SK-SD into the body can cause sensitized lymphocytes in the body to cause delayed type hypersensitivity, causing lymphocytes and monocytes to infiltrate, showing local redness and swelling, thereby detecting the cellular immune function of the body. Reagents: Streptokinase-chain enzymes each contained SK40u and SD10u/ml or each contained SK400u and SD100u/ml. The high concentration is used to determine the fibrinolytic activity. When diluted to a certain concentration, the fibrinolytic activity is not significantly preserved. Operation method: (1) Take SK-SD1ml and dilute with physiological saline to contain SK4u and SD1u per 0.1ml. Use a 1ml syringe to extract an appropriate amount of the above solution into the forearm and inject 0.1ml into the skin to form a white vesicle. (2) After 48 hours, the skin reaction was observed, and the average value of the induration diameter was greater than 5 mm. If the reaction is negative, you can use the second intensity, that is, every 10ml containing SK40u, SD10u for retesting, sometimes a positive result. Not suitable for the crowd There is no inappropriate crowd. Adverse reactions and risks It is a safe check and is harmless to the body.

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