skin test

Skin tests are the most commonly used specific tests, including patches, scratches, spurs, and intradermal injections. It is most commonly used in clinical trials for picking and intradermal tests, such as a negative test; it can be used for intradermal test. Method and principle Specific patient exposure to allergens can induce the production of specific IgE, which adheres to the IgE receptor on the surface of the mast cells of the skin or submucosa, when it meets with allergens entering the body again. The bridging of two allergens with two IgE antibodies causes a series of biochemical processes in the mast cells, releasing allergic mediators, creating wheals, blushing or itching in the skin. On the inside of the patient's forearm, routine disinfection, and then use OT syringe, No. 4 injection needle to inhale different kinds of allergen infusion solution into the forearm medial skin 0.02ml, the distance between antigen points is 2.5cm. After 15 to 20 minutes of skin test, skin reactions, local wheal and blush size were observed and compared with control points. Basic Information Specialist classification: skin examination classification: immune examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: abnormal. Tips: The patient stopped taking antihistamines and corticosteroids 24 to 48 hours before the skin test, but did not need to stop taking asthma. Normal value Negative no papules and redness, or very slight redness. Clinical significance As a result, it was judged that the positive reaction of the puncturing test was mainly blush, and the positive reaction of the intradermal test was mainly wheal. 1. Negative no papules and redness, or very slight redness. 2. Suspicious redness is less than 0.5cm. 3. Positive wind group with red halo 0.5; wind group with red halo 0.5~1.0cm; wind group with red halo is larger than 1cm but no pseudopod; wind group with red halo is larger than 1.5cm, and there is pseudopod. Positive results are seen in allergic diseases. Positive results may be diseases: clonorchiasis, contact dermatitis, hay fever, millet rash, erythema pemphigus, leukoplakia, cercariae dermatitis, body lice, allergic dermatitis, pediatric food allergies Things to be aware of in skin tests: 1. The paralyzed patient stopped taking antihistamines and corticosteroids 24 to 48 hours before the skin test, but did not need to stop taking asthma. 2. In the skin test, in addition to observing the local immediate reaction, it should also pay attention to the patient's systemic reaction such as chest tightness, shortness of breath, pale complexion, cold sweat, and itchy skin rash. Once found, it should be treated promptly to avoid danger. 3. When the patient comes home, continue to observe whether there is a late reaction within 72 hours. 4. For those who are highly sensitive to suspected allergens, try not to do an intradermal test to avoid accidents. Inspection process Inspection method: On the inner side of the patient's forearm, routinely disinfect, then use OT syringe, No. 4 injection needle to inhale different kinds of allergen infusion solution into the inner skin of the forearm and 0.02ml, the distance between antigen points is 2.5cm. After 15 to 20 minutes of skin test, skin reactions, local wheal and blush size were observed and compared with control points. Not suitable for the crowd There are no special taboos. Adverse reactions and risks There are no related complications and hazards.

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