Indirect fluorescent antibody absorption test for leprosy (FLA-ABS test)

In recent years, with the advancement of immunology, some new methods have been introduced in the diagnosis of leprosy, mainly the fluorescent leprosy antibody absorption test (referred to as FLA-ABS test). This is an indirect immunofluorescence technique, its basic principle and The fluorescent Treponema pallidum antibody uptake assay was consistent. It uses M. leprae as an antigen to detect the presence of antibodies against M. leprae specific antigen in human serum. Basic Information Specialist classification: Infectious disease examination and classification: immunological examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Most types of active leprosy are positive. Tips: Please inform the doctor about the recent medication and special physiological changes before the test. Normal value negative. Clinical significance Abnormal results showed that the fluorescence of the ++ reaction was positive. Most types of active leprosy are positive. A positive indicates a clinical infection with leprosy. The positive rate of multi-bacterial leprosy was about 0.95 (95%), and the positive rate of leprosy with little bacteria was about 0.80 (80%). For example, both intradermal test and fluoroscopy are positive, indicating that although there is leprosy infection, effective defense immunity has been established. Most patients will stop in the subclinical stage, and a few can develop leprosy. If the skin test is negative, the fluorescent antibody is positive, indicating that it has been infected by leprosy, but an effective cellular immune response has not been established. If the skin test continues to be negative, it may develop into a multi-bacterial leprosy. Need to check the crowd chills, fever, etc. In addition, there may be a variety of tissue and organ symptoms such as neuritis, arthritis, lymphadenitis, rhinitis, iridocyclitis, testicular epididymitis, humeral periostitis, nephritis and hepatosplenomegaly. crowd. Positive results may be diseases: leprosy, syphilis precautions Abnormal people: generally no special population. Forbidden before examination: Please inform the doctor about the recent medication and special physiological changes before the test. 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. Requirements for examination: When taking blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Inspection process Inspection method: Using M. leprae as an antigen, detect whether there is an antibody against the specific antigen of M. leprae in human serum. Not suitable for the crowd There are no special taboos. Adverse reactions and risks No related complications and hazards.

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