Potassium perchlorate release test

The potassium perchlorate release test is an examination of oral potassium perchlorate, a regular rate of I, and a normal judgment of thyroid function. The 3-hour thyroid excretion rate was (16.1±19.3)% (range 18.6% to 16.7%), and the abnormality was generally greater than 10% (the result of thyroid site measurement after taking iodine for 2 hours was 100%, and potassium chlorate was administered for 1 hour). After the second injection rate, calculate the 3-hour thyroid discharge rate). Basic Information Specialist classification: growth and development check classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Tips: Pay attention to the normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Normal value The 3-hour thyroid excretion rate was (16.1±19.3)% (range 18.6% to 16.7%), and the abnormality was generally greater than 10% (the result of thyroid site measurement after taking iodine for 2 hours was 100%, and potassium chlorate was administered for 1 hour). After the second injection rate, calculate the 3-hour thyroid discharge rate). Clinical significance Abnormal results: If the second iodine intake rate is not significantly lower than the first time (ie, the 3-hour discharge rate is <10%), the organic function of the thyroid is normal. If the second iodine intake rate is significantly lower than the first time (ie, the 3-hour discharge rate is >10%), it indicates that there is a defect in the thyroid organic function, which is common in deafness, goiter syndrome, and goiter-like sporadic cretin. Disease, chronic lymphocytic thyroiditis and iodized goiter. People who need to be examined: goiter syndrome, goiter-like sporadic cretinism, chronic lymphocytic thyroiditis, and iodized goiter. High results may be diseases: chronic autoimmune thyroiditis, chronic lymphocytic thyroiditis in children, chronic lymphocytic thyroiditis Forbidden before examination: pay attention to normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Requirements for inspection: Actively cooperate with the doctor's request. This test is taking anti-thyroid drugs (such as thiourea, tazobactam, PAS, D860, etc.), and patients with hyperthyroidism after taking I can also be positive. Inspection process Subjects were given an oral dose of iodine on an empty stomach (eg, simultaneous administration of 15 mg/kg body weight of potassium chloride or 300 μg/m orally, which increased the sensitivity of the test, referred to as the iodine perchlorate test). After 2 hours, the first iodine uptake rate of the thyroid gland was measured. Following oral administration of potassium perchlorate (KClO4) 400 micrograms, 1 hour later, the iodine rate was measured, and the thyroid function was normal. The second measured iodine intake rate did not decrease significantly compared with the first time. When certain diseases caused tyrosine iodine When the resistance was blocked, the iodine uptake rate was measured again and decreased significantly compared with the first time. Not suitable for the crowd Inappropriate crowd: temporarily unknown. Adverse reactions and risks No related complications or hazards.

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