Viper venom phospholipid setting time

In the RVVCT test, a medium amount of cerebral phospholipid suspension was used to observe the time required for blood coagulation to know whether the patient's blood coagulation factor was defective. The application of venom phospholipid time method in the monitoring of low molecular weight heparin can be applied to the principle of venom specific inhibitor Xa, and the content of venom, the amount of phospholipid and the bath time are adjusted, and the specificity and sensitivity are established. It is simple and convenient, and is suitable for the quantitative determination of plasma low molecular weight heparin in routine laboratory use. Basic Information Specialist classification: skin examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: When you take blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Normal value 9.5 ± 1.2 s. Clinical significance Abnormal result (1) Both RVVCT and RVVRT are prolonged, indicating a lack of factor X. (2) RVVCT is normal and RVVRT is prolonged, indicating lack of PF3. (3) Both RVVCT and RVVRT were normal, while PT was prolonged, indicating a lack of factor VII. (4) RVVCT prolongation, found in congenital or acquired fibrinogen, prothrombin, factor V, X deficiency. Low-molecular-weight heparin is measured in patients with diseases associated with clotting factor deficiency. High results may be diseases: digestive system cancer with blood disease syndrome Contraindications before examination: When taking blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Requirements for inspection: The venom dilution is unstable. If carbonic acid is added, it can be stored at 4 °C. If it is not added, it should be stored at -20 °C for about 20 days. Inspection process A certain amount of blood needs to be taken for testing, and a medium amount of cerebral phospholipid suspension is used to observe the time required for blood to coagulate. Not suitable for the crowd A patient with hemophilia and severe clotting factor deficiency. Adverse reactions and risks Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection.

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