erythrocyte glucose-6-phosphate dehydrogenase activity

Erythrocyte glucose-6-phosphate dehydrogenase activity refers to the activity of glucose-6-phosphate dehydrogenase, an enzyme that measures red blood cell energy metabolism. The metabolism of red blood cells requires the participation of a variety of enzymes, and any one of the enzyme defects can cause hemolysis. Most of the so-called enzyme defects are genetic defects, and abnormal genes cause abnormal structure of the enzyme molecule to form an enzyme having no normal function. There are many types of enzyme deficiency, mainly glucose-6-phosphate dehydrogenase and pyruvate kinase defects. Defects in glucose-6-phosphate dehydrogenase cause red blood cell metabolism disorders and shorten their lifespan. Basic Information Specialist classification: cardiovascular examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. Normal value Colorimetric method 2.8 ~ 7.3U / gHb. Fluorescent spots have fluorescent spots. Clinical significance Abnormal results: The activity of glucose-6-phosphate dehydrogenase is measured clinically for the differential diagnosis of hemolytic anemia. In patients with glucose-6-phosphate dehydrogenase deficiency, drug reactions (such as primaquine, sulfapyridine, acetanilide, etc.), faba bean disease, infection, etc., the activity of glucose-6-phosphate dehydrogenase is decreased. The people who need to be examined have dizziness, headache, palpitations, difficulty breathing, abdominal pain, low back pain and other symptoms. Low results may be diseases: precautions for glucose-6-phosphate dehydrogenase deficiency First, the precautions before blood draw: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the physical examination, fasting should be given to ban drugs that can degrade hemoglobin, such as sulfonamides and primaquine. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, after blood draw should pay attention to: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process The examination process: blood is drawn, blood is taken for examination, and venous blood is generally taken, and blood is drawn by a doctor or a nurse. The amount of blood drawn is determined according to the difference of the test content and the number of items. The blood volume is usually 2-20 ml, and the maximum is not more than 50 ml. Enzyme specific examination is then used by the physician. Not suitable for the crowd Hemophilia and diffuse intravascular coagulation. Adverse reactions and risks Risk of infection: If you use an unclean needle, you may be at risk of infection.

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