erythrocyte phosphofructokinase
Erythrocyte enzymes play an important role in regulating red blood cell metabolism. TPI is an isomerase in cell lysosomes. Enzyme deficiency leads to a decrease in energy supply, and shortened red blood cell life leads to hemolytic anemia. Basic Information Specialist classification: cardiovascular examination classification: biochemical examination Applicable gender: whether men and women apply fasting: not fasting Tips: When you take blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Normal value (1) Adult: The customary unit is 9.05±1.89U/gHb(±s). 262 ± 55 U/1012 RBC (± s). 3.08 ± 0.64 U / ml RBC (± s). The legal unit is 0.58 ± 0.12 mU / molHb (± s). 0.26 ± 0.05 nU / RBC (± s). 3.08 ± 0.64 kU / LRBC (± s). (2) Newborn results are low. Clinical significance Abnormal results: (1) Phosphofructokinase activity is reduced in muscle dysfunction caused by type VII glycogen accumulation. (2) PFK deficiency can lead to aspheric erythrocyte hemolytic anemia. The people who need to be examined have people who have a sudden onset of illness, sudden chills, high fever, pale complexion, back pain, shortness of breath, fatigue, and irritability. Precautions Before inspection: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. After inspection: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process The examination process: blood is drawn, blood is taken for examination, and venous blood is generally taken, and blood is drawn by a doctor or a nurse. The amount of blood drawn is determined according to the difference of the test content and the number of items. The blood volume is usually 2-20 ml, and the maximum is not more than 50 ml. Then the doctor performs protein color test. Not suitable for the crowd Have a coagulopathy such as hemophilia. Adverse reactions and risks Bleeding: After blood collection, use sterile cotton lump or other disinfecting hemostatic articles to tighten the needle to stop bleeding, especially for patients with coagulopathy should be given sufficient time to avoid bleeding.
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