Lysine

Lysine is the basic unit of protein, and is one of the 21 kinds of amino acids that make up human proteins. The amino acids are all amino acids except the amino acids. The amino acids constituting the protein molecule are all L-amino acids, but in recent years it has been confirmed that they can be isomeric as D-amino acids, and the specific mechanism has not been studied. Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Rare. Normal value: Lysine (fluorescence assay): 188.68-272.32 μmol/L Above normal: High lysineemia. negative: Positive: Tips: Do not wear clothes that are too small or too tight, so as to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Normal value Fluorescence assay: 188.68 ~ 272.32 μmol / L. Clinical significance Abnormal results Lysine is an essential amino acid and belongs to a dibasic amino acid. The final metabolite is primarily acetyl-CoA in the presence of alpha-ketoglutarate. From yeast to a-aminoabidonic acid. The main metabolic pathway of lysine is the production of yeast. There are also metabolic pathways that convert to homo-proline and homo-arginine, but in small amounts. The metabolic disorder of lysine is a decrease in α-ketoglutarate reductase, which may be autosomal recessive. The main symptoms of persistent high lysineemia are convulsions, mental retardation, developmental disorders, hypotonia, and ligament relaxation. In addition to increased lysine excretion in the urine, there are also increased excretions of ornithine, ethanolamine, homoproline, homoarginine, and hexahydropyridine. High lysineemia accompanied by glutamateuria, urinary excretion of lysine, proline, homo-proline and M-aminoadipate, and lactosine in serum and urine Lysine and proline in blood can be increased to 4 to 5 times of normal. In the case of hydroxylysineuria, hydroxylysine is excreted in the urine, but the site of metabolic disorders is unknown. Need to check the population of malnourished people. Precautions Inappropriate people: generally no special population. Taboo before the examination: It is necessary to cooperate with the doctor to write the correct name, neat and tidy, to avoid confusion caused by the same name or similar names. With these in mind, blood draws are more convenient and faster, and you can better save yourself time for diagnosis. Requirements for inspection: Do not wear clothes that are too small or too tight in cuffs to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Different laboratory items should be asked by the doctor and treated differently. Inspection process A widely used lysine production method. The commonly used raw materials are cheap sugar raw materials such as waste molasses and starch hydrolyzate after sugar cane or sugar beet. In addition, acetic acid, ethanol and the like are also available raw materials. The main microorganisms for producing lysine by direct fermentation include three kinds of strains such as Corynebacterium glutamicum, Brevibacterium flavum, and Brevibacterium lactofermentum. This method was developed in the late 1950s. Since the 1970s, due to the progress of breeding technology, some mutant strains with multiple genetic markers have been selected, which has made the process mature and the production of lysine has doubled. The highest acid yield in industrial production has been increased to 100-120g per liter of fermentation broth, and the extraction rate is about 80-90%. Not suitable for the crowd no. Adverse reactions and risks no.

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