erythrocyte aldolase

Aldolase is a general term for a class of enzymes that catalyze aldol condensation, and is one of the important enzymes in the process of carbohydrate metabolism in vivo. It is widely distributed in human tissues, with the largest number in the heart and liver. The main function is to decompose fructose 1,6 diphosphate into dihydroxyacetone phosphate and glyceraldehyde-3-phosphate, and to decompose fructose 1-phosphate into dihydroxyacetone phosphate and glyceraldehyde. ALD is highly contained in red blood cells and platelets, so specimens should be taken to avoid hemolysis. Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Can be seen in some patients with congenital non-spherical erythrocyte hemolytic anemia. Normal value: Red blood cell aldolase (adult): 0.15-0.27mU/molHb Above normal: Rare. negative: Positive: Tips: After 8 pm on the day before the medical examination, you should start fasting for 12 hours, so as not to affect the test results. Normal value 1, customary units Adult 3.194 ± 0.86 U / g Hb (± s). 92 ± 24.9 U / 1012 RBC (± s). 1.08 ± 0.29 U / ml RBC (± s). 2. Legal unit; Adult 0.21 ± 0.06 mU / mol Hb (± s). 0.09 ± 0.02 nU / RBC (± S). 1.08 ± 0.29 kU / LRBC (± s). 3. The neonatal outcome is significantly higher. Clinical significance Aldolase deficiency can be seen in some patients with congenital non-spherical erythrocyte hemolytic anemia. Low results may be diseases: precautions for hemolytic anemia in children Before inspection: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. After inspection: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process The examination process: blood is drawn, blood is taken for examination, and venous blood is generally taken, and blood is drawn by a doctor or a nurse. The amount of blood drawn is determined according to the difference of the test content and the number of items. The blood volume is usually 2-20 ml, and the maximum is not more than 50 ml. Enzyme specific examination is then used by the physician. Not suitable for the crowd no. Adverse reactions and risks no.

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