granule membrane protein-140
The occurrence of many diseases is related to the activation of platelets. During the activation process, not only the morphological and biochemical metabolism changes, but also the structure and composition of membrane proteins. Platelet α-granule membrane protein is one of the specific markers of platelet activation and release, which can reflect the activation degree of platelets and the tendency of thrombosis in vivo. It provides a new way for the early diagnosis and treatment of human thrombotic diseases, and diagnoses other diseases. It also has important value. Basic Information Specialist classification: cardiovascular examination classification: biochemical examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Rare. Normal value: Granular membrane protein-140:720.63-1148.57 Above normal: 1. Significantly increase the epidemic hemorrhagic fever and oliguria. 2, generally elevated epidemic hemorrhagic fever and polyuria. negative: Positive: Tips: Do not wear clothes that are too small or too tight, so as to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Normal value The average molecular number of the monoclonal antibody SZ-51 assay was 720.63 to 1148.57. Clinical significance Abnormal result 1. Significantly increase the epidemic hemorrhagic fever and oliguria. 2, generally elevated epidemic hemorrhagic fever and polyuria. Need to check the pregnant women in the population, suspected kidney disease, early diagnosis of thrombotic diseases. High results may be diseases: precautions for epidemic hemorrhagic fever Inappropriate people: generally no special population. Taboo before the examination: It is necessary to cooperate with the doctor to write the correct name, neat and tidy, to avoid confusion caused by the same name or similar names. With these in mind, blood draws are more convenient and faster, and you can better save yourself time for diagnosis. Requirements for inspection: Do not wear clothes that are too small or too tight in cuffs to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Different laboratory items should be asked by the doctor and treated differently. Inspection process Solid phase sandwich enzyme-linked immunosorbent assay (ELISA). Standards with unknown concentrations of GMP-140 and samples of unknown concentration are added to the microplates for detection. GMP-140 and biotinylated antibodies were first incubated simultaneously. After washing, avidin-labeled HRP was added. After incubation and washing, the unbound enzyme conjugate is removed, then the substrates A, B, and the enzyme conjugate are added simultaneously. Produce color. The depth of the color is proportional to the concentration of GMP-140 in the sample. Not suitable for the crowd no. Adverse reactions and risks no.
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