A fetal globulin test

Alpha-fetoprotein (AFP) is a single peptide glycoprotein composed of 590 amino acids. It is an embryonic protein mainly produced by embryonic liver cells and yolk sac. The mucosa of the gastrointestinal mucosa can also be produced. A small amount. The concentration of AFP drops rapidly after birth and is close to the adult level within a few months to a year. Its amino acid sequence has great homology with human serum albumin, and the genes of both are located on the same DNA strand. Normal liver cells do not produce AFP but synthesize albumin. When hepatocytes become cancerous, AFP is re-expressed. Basic Information Specialist classification: Digestive examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: Before the inspection: adjust the body, the diet is regular, and the schedule is good. Normal value Radioimmunoassay <10μg/L. ELISA <25 μg / L. Rocket electrophoresis autoradiography <20μg / L. Clinical significance Abnormal result 1, under normal circumstances, acute hepatitis, cirrhosis, most AFP <300μg / L; and 60% of hepatocellular carcinoma, testicular cancer, non-sperm cell germ cell tumor case AFP> 1000μg / L. 2, AFP increased in pregnant women after 3 months of pregnancy, peaked in 7 to 8 months, generally below 400μg / L. AFP returned to normal 3 weeks after delivery. If the serum AFP of pregnant women is abnormally elevated, fetal spina bifida, no brain, hydrocephalus, renal degeneration, threatened abortion should be considered. People with abnormal liver function who need to be tested. High results may be diseases: spina bifida, no brain notes Before the examination: adjust the body, the diet is regular, and the schedule of work and rest is good. When inspecting: Follow the doctor's instructions. Not suitable for the crowd: no. Inspection process Blood test, immunological or rocket electrophoresis autoradiography. Not suitable for the crowd no. Adverse reactions and risks no.

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