α2-HS-glycoprotein

α2-HS, also known as thermostable glycoprotein, is mostly synthesized by the liver and is a component of the bone matrix. The half-life in blood is 4 to 5 days. The immunoelectrophoresis position is slightly faster than binding to globin, between the Gc globulin and the haptoglobin. Basic Information Specialist classification: Digestive examination classification: biochemical examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Serum α2-HS was significantly reduced in negative acute phase reaction protein infection, major surgery, malignant tumor, and malnutrition. Normal value: α2-HS-glycoprotein (immuno diffusion method): 400-850mg/L Above normal: α2-HS is elevated in acute hepatitis and persistent hepatitis, and some show no significant change in acute hepatitis. negative: Positive: Tips: Before the examination, the diet is light and alcohol is prohibited. Check for an empty stomach in the morning. Normal value 1. Immunodiffusion method: Serum 400 ~ 850mg / L, the average value of 600mg / L. 2. Immunoelectrophoretic diffusion method. The 5% to 95% percentile of urine is 0.07 to 1.12 mg/24h. Cerebrospinal fluid 11.7mg / L. Clinical significance 1. Diagnosis of liver disease diagnosis and prognosis The literature reports that the changes of serum α2-HS in patients with acute hepatitis are inconsistent. Some experimental results show that α2-HS is elevated in acute hepatitis and persistent hepatitis, and some show no significant change in acute hepatitis, but decrease significantly in subacute hepatic necrosis. It was found that the serum α2-HS of patients with subacute hepatic necrosis was significantly lower than that of survivors. Therefore, serum α2-HS determination is helpful for early diagnosis of subacute hepatic necrosis and judgment of severity and prognosis of liver damage. 2. Serum α2-HS was significantly decreased in negative acute phase reaction protein infection, major surgery, malignant tumor and malnutrition. Low results may be diseases: high hepatitis results may be diseases: precautions for malnutrition It is known that α2-HS molecules exist in both N and L forms. Very sensitive to proteolytic enzymes. At present, its physiological function is not clear, and it has been proved that α2-HS can reduce the response of lymphocytes to plant lectins and promote the conditioning effect. Inspection process The same as the immunodiffusion method. Not suitable for the crowd no. Adverse reactions and risks no.

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