Anti-SS-A and SS-B antibodies

Discovery and nomenclature of anti-SS-A and anti-SS-B antibodies In 1961, Anderson et al. Identified two antibodies with different immunological properties in the sera of patients with Sjogren's syndrome (SS), called SjT and SjD antibodies, respectively. Later, Reichlin and others found similar two antibodies in the serum of patients with systemic lupus erythematosus (SLE), named Ro and La antibodies, respectively. In 1975, Alspangh and Tan et al. Studied the activity of these two new antibodies in the serum of SS patients, and called the two antibodies SS-A and SS-B antibodies. Relevant international laboratories exchanged sera. In 1979, it was finally confirmed that SS-A was actually Ro and SS-B was La.

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