Gram-positive cocci and Gram-negative scleritis

Infectious scleritis Inflammation of the sclera tissue caused by pathogen infection. This inflammation can be caused by a direct invasion of the pathogen or by an allergic reaction from the pathogen. The infection pathways of infectious scleritis can be divided into two types: exogenous and endogenous. Exogenous infections are usually caused directly by trauma, surgery, or infections of tissues adjacent to the sclera. Endogenous infections can be caused by systemic infectious diseases (including those caused by purulent pathogens or non-purulent granulomatous pathogens) such as tuberculosis, leprosy, and syphilis through the circulatory system. Infectious scleritis can be controlled by special treatment, and glucocorticoids and immunosuppressants commonly used in the treatment of non-infectious scleritis related to immune diseases are contraindicated in the treatment of active infectious scleritis. Generally speaking, the use of glucocorticoids and immunosuppressants alone can exacerbate the damage of infectious scleritis, spread the microorganisms, and worsen the disease. However, if the infectious scleritis is considered to be immune, with the support of effective antibiotics, careful local or systemic use of glucocorticoids and immunosuppressants is still necessary.

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