Pediatric androgen insensitivity syndrome

Androgenin sensitivity syndrome (AIS) in children is a clinically common single-gene developmental disorder. A variety of clinical manifestations result from the complete or partial loss of the normal effects of androgens, ranging from complete female phenotypes to under-masculine or infertile male phenotypes, the most common of male pseudohermaphroditisms. The disease occurs in people with a karyotype of 46, XY. The X-linked recessive inheritance in AIS occurs in the same family.

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