Fat embolism syndrome

Fat embolism syndrom (FES) is a complication of serious injuries such as trauma and fracture. Since Zenker first discovered fat droplets from the pulmonary vascular bed of severe trauma death cases in 1882 and Bergmann's first clinical diagnosis of fat embolism in 1887, although it has been a century, many people have studied from different perspectives, but due to its clinical manifestations The differences are very large, some cases are fierce, the disease is rapid, and they die quickly even before the typical symptoms appear, and some may not have obvious clinical symptoms, but only found after autopsy after death. Therefore, it was not until the last 20 years that there was any further understanding of its pathophysiology. Bagg (1979) and others believe that this syndrome is a post-traumatic respiratory distress syndrome that occurs within 72 hours after a fracture. Early trauma, such as tachycardia, elevated body temperature over 38 ° C, decreased arterial oxygen pressure (PaO2), and special signs such as blizzard shadows in the lungs, can be diagnosed. Broder believes that in addition to injuries, burns, metabolic disorders, decompression sickness, connective tissue disease, severe infections, new organisms, and osteomyelitis can also induce FES.

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