Clonorchiasis sinensis

Clonorchiasis sinensis, also known as liver fluke disease, Chinese clonorchiasis, is a disease caused by clonorchiasis sinensis (branch fluke). It is mainly caused by ingestion of immature freshwater fish. The clinical manifestations are mainly chronic digestive dysfunction, pain in the liver area and liver enlargement, and severe cases can cause liver cirrhosis. It is also often accompanied by biliary tract infection, cholecystitis, cholelithiasis, and bile duct cell carcinoma. The disease is distributed in Asia and is more common in China, Japan, North Korea and other countries. An estimated 19 million people are infected worldwide. A 1984 study of the ancient Han corpse in Jiangling, Hubei, China showed that the disease existed in China as early as 2300 years ago. It is now distributed in 24 provinces, municipalities and autonomous regions in South China, Southwest China, North China and Northeast China. The population infection rate is about 0.1 to 57.0%. In particular, residents of Guangdong and other provinces have the habit of eating "fish raw" and "fish raw porridge" and are more susceptible to infection.

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