Persistent severe pain in the right upper quadrant and radiation to the right shoulder

Persistent severe pain in the right upper quadrant and radiation to the right shoulder is one of the symptoms of acute cholecystitis. Acute cholecystitis is inflammation of the gallbladder caused by obstruction of the gallbladder duct and bacterial invasion; its typical clinical feature is paroxysmal colic in the right upper abdomen, accompanied by marked tenderness and abdominal rigidity.

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