Increased glomerular volume

The increase in glomerular volume refers to the physiological and pathological characteristic morphological changes of the glomeruli due to lipoprotein glomerulopathy. Lipoprotein glomerulopathy is a kidney disease that is characterized by the presence of lipoprotein emboli in the glomerular capillaries and the absence of extrarenal lipoprotein embolism. Lipoprotein glomerulopathy is more common in men, with a male to female ratio of 15: 8; the average age of onset is 32 years (4 to 49 years). Most cases are sporadic, and a few are familial. Lipoprotein glomerulopathy is a kidney disease that is characterized by the presence of lipoprotein emboli in the glomerular capillaries and the absence of extrarenal lipoprotein embolism. The clinical manifestations are similar to type III hyperlipidemia with elevated plasma apolipoprotein E (apoE). The disease was first reported by SaitoT and others at the 17th Annual Meeting of the Japanese Society of Nephrology in 1987. In 1989, Sakaguchi and others proposed the disease as an independent glomerular disease based on the clinical manifestations and pathological characteristics of the patient. The disease was named lipoprotein glomerulopathy in the same year. However, lipoprotein glomerulopathy does not improve glomerular disease through hypolipidemic treatment. At present, this disease is considered to be a rare disease of glomerular type III that is limited to the kidney with lipid deposition.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.